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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ROBO3 All Species: 19.09
Human Site: S923 Identified Species: 42
UniProt: Q96MS0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96MS0 NP_071765.2 1386 148209 S923 R K Q R K E L S H Y T A S F A
Chimpanzee Pan troglodytes XP_001144482 1395 153226 S908 R K K R K G L S N Y A V T F Q
Rhesus Macaque Macaca mulatta XP_001106913 1300 139057 L864 S A P V L V Q L P S P P D L E
Dog Lupus familis XP_546425 1385 148148 S924 R R Q R K E L S H Y T A S F A
Cat Felis silvestris
Mouse Mus musculus Q9Z2I4 1366 146035 S923 Q K Q R K E L S H Y T A S F A
Rat Rattus norvegicus O55005 1651 180729 N993 S H N D C S I N C C T A S N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512208 1575 172904 S887 R K K R K G L S N Y A V T F Q
Chicken Gallus gallus XP_416674 1403 153767 S890 R K K R K G L S N Y A V T F Q
Frog Xenopus laevis NP_001084250 1614 176716 L986 I A N Y N N Q L D S K Q T N L
Zebra Danio Brachydanio rerio Q7ZW34 1056 116184 P627 E L L V R G P P G P P G V V I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726224 1429 155803 K977 S M V Y F K R K H Q M T K E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.9 90.9 90.3 N.A. 80.5 38.6 N.A. 40.7 42 39.2 20.3 N.A. 27.4 N.A. N.A. N.A.
Protein Similarity: 100 58.1 91.8 93.4 N.A. 85.9 53.4 N.A. 55.6 57 54 35.4 N.A. 42.2 N.A. N.A. N.A.
P-Site Identity: 100 53.3 0 93.3 N.A. 93.3 20 N.A. 53.3 53.3 0 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 73.3 0 100 N.A. 100 33.3 N.A. 73.3 73.3 6.6 6.6 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 0 0 0 0 0 28 37 0 0 28 % A
% Cys: 0 0 0 0 10 0 0 0 10 10 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 10 0 0 0 10 0 0 % D
% Glu: 10 0 0 0 0 28 0 0 0 0 0 0 0 10 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 55 0 % F
% Gly: 0 0 0 0 0 37 0 0 10 0 0 10 0 0 10 % G
% His: 0 10 0 0 0 0 0 0 37 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % I
% Lys: 0 46 28 0 55 10 0 10 0 0 10 0 10 0 0 % K
% Leu: 0 10 10 0 10 0 55 19 0 0 0 0 0 10 19 % L
% Met: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 19 0 10 10 0 10 28 0 0 0 0 19 0 % N
% Pro: 0 0 10 0 0 0 10 10 10 10 19 10 0 0 0 % P
% Gln: 10 0 28 0 0 0 19 0 0 10 0 10 0 0 28 % Q
% Arg: 46 10 0 55 10 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 28 0 0 0 0 10 0 55 0 19 0 0 37 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 37 10 37 0 0 % T
% Val: 0 0 10 19 0 10 0 0 0 0 0 28 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 19 0 0 0 0 0 55 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _