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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF145
All Species:
10.91
Human Site:
T617
Identified Species:
21.82
UniProt:
Q96MT1
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MT1
NP_653327.1
663
75617
T617
E
P
P
G
Q
E
H
T
P
G
T
R
I
Q
E
Chimpanzee
Pan troglodytes
XP_518069
702
79985
T656
E
P
P
G
R
E
H
T
P
G
T
R
I
Q
E
Rhesus Macaque
Macaca mulatta
XP_001082926
688
78619
T642
E
P
P
G
Q
E
H
T
P
G
T
R
I
Q
E
Dog
Lupus familis
XP_546272
670
76347
P617
E
P
P
N
Q
E
H
P
P
G
T
R
M
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWK7
663
74629
P617
E
P
P
D
H
E
S
P
P
G
T
G
T
Q
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506623
680
76969
P617
D
P
P
G
V
D
H
P
A
G
R
N
V
S
G
Chicken
Gallus gallus
XP_001233173
684
76990
D617
E
P
P
G
A
E
Q
D
S
G
P
N
T
G
D
Frog
Xenopus laevis
Q5BIY5
695
78476
E650
V
E
R
R
G
E
L
E
V
H
V
S
Q
E
E
Zebra Danio
Brachydanio rerio
Q7ZWF4
685
77631
T618
Q
P
Q
V
E
L
N
T
E
E
G
I
R
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRW1
809
89216
P717
V
E
A
S
E
Q
A
P
A
T
S
S
S
S
A
Honey Bee
Apis mellifera
XP_392068
661
75864
R610
Y
F
H
S
V
C
L
R
K
W
L
Y
V
Q
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786512
686
76228
D617
A
Q
P
G
A
G
G
D
A
N
S
D
A
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
92.3
95.6
N.A.
93.8
N.A.
N.A.
89.1
87.5
81.7
77.9
N.A.
23.8
28.6
N.A.
36.5
Protein Similarity:
100
94.4
93.9
96.5
N.A.
95.7
N.A.
N.A.
91.4
90.6
86.6
85.2
N.A.
43.6
50.8
N.A.
59.3
P-Site Identity:
100
93.3
100
80
N.A.
60
N.A.
N.A.
33.3
40
13.3
20
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
60
N.A.
N.A.
53.3
46.6
20
40
N.A.
20
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
17
0
9
0
25
0
0
0
9
17
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
9
0
17
0
0
0
9
0
0
17
% D
% Glu:
50
17
0
0
17
59
0
9
9
9
0
0
0
9
59
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
50
9
9
9
0
0
59
9
9
0
9
9
% G
% His:
0
0
9
0
9
0
42
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
25
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
17
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
9
0
17
0
0
0
% N
% Pro:
0
67
67
0
0
0
0
34
42
0
9
0
0
0
0
% P
% Gln:
9
9
9
0
25
9
9
0
0
0
0
0
9
50
0
% Q
% Arg:
0
0
9
9
9
0
0
9
0
0
9
34
9
0
0
% R
% Ser:
0
0
0
17
0
0
9
0
9
0
17
17
9
17
9
% S
% Thr:
0
0
0
0
0
0
0
34
0
9
42
0
17
0
0
% T
% Val:
17
0
0
9
17
0
0
0
9
0
9
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _