Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRICKLE1 All Species: 31.21
Human Site: S318 Identified Species: 76.3
UniProt: Q96MT3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96MT3 NP_001138353.1 831 94300 S318 D V H A S D S S D S A F Q S A
Chimpanzee Pan troglodytes XP_509007 831 94309 S318 D V H A S D S S D S A F Q S A
Rhesus Macaque Macaca mulatta XP_001089576 1098 122550 S576 D P N G S D S S D S A F Q N A
Dog Lupus familis XP_534833 832 94436 S318 D V H A S D S S D S A F Q S A
Cat Felis silvestris
Mouse Mus musculus Q3U5C7 832 94113 D319 I H A S D S S D S A F Q S A R
Rat Rattus norvegicus Q71QF9 831 94152 S318 D I H A S D S S D S A F Q S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505284 1127 125621 S610 D V H A S D S S D S A F Q S A
Chicken Gallus gallus XP_416036 828 94179 S314 D V H A S D S S D S A F Q S A
Frog Xenopus laevis Q90WV2 832 94675 S318 D V H A S D S S D S A F Q S A
Zebra Danio Brachydanio rerio NP_899185 793 90017 A289 T D A C F S C A Q C K S S L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 40 97.1 N.A. 93.1 93.2 N.A. 64.4 87.9 80.7 67.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 50.4 98.8 N.A. 96.5 96.9 N.A. 69.2 93.7 90.2 78.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 73.3 100 N.A. 6.6 93.3 N.A. 100 100 100 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 100 N.A. 26.6 100 N.A. 100 100 100 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 70 0 0 0 10 0 10 80 0 0 10 80 % A
% Cys: 0 0 0 10 0 0 10 0 0 10 0 0 0 0 0 % C
% Asp: 80 10 0 0 10 80 0 10 80 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 10 80 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 70 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 10 80 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 0 0 10 80 20 90 80 10 80 0 10 20 70 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _