KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE1
All Species:
30.91
Human Site:
Y250
Identified Species:
75.56
UniProt:
Q96MT3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MT3
NP_001138353.1
831
94300
Y250
F
E
S
L
Y
A
E
Y
C
E
T
C
G
E
H
Chimpanzee
Pan troglodytes
XP_509007
831
94309
Y250
F
E
S
L
Y
A
E
Y
C
E
T
C
G
E
H
Rhesus Macaque
Macaca mulatta
XP_001089576
1098
122550
Y508
F
E
S
L
Y
A
E
Y
C
D
T
C
A
Q
H
Dog
Lupus familis
XP_534833
832
94436
Y250
F
E
S
L
Y
A
E
Y
C
E
A
C
G
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3U5C7
832
94113
C251
E
S
L
Y
A
E
Y
C
E
T
C
G
E
H
I
Rat
Rattus norvegicus
Q71QF9
831
94152
Y250
F
E
S
L
Y
A
E
Y
C
E
T
C
G
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505284
1127
125621
Y542
F
E
S
L
Y
A
E
Y
C
E
S
C
G
E
H
Chicken
Gallus gallus
XP_416036
828
94179
Y246
F
E
S
L
Y
A
E
Y
C
E
T
C
G
E
H
Frog
Xenopus laevis
Q90WV2
832
94675
Y250
F
E
S
H
Y
A
E
Y
C
E
S
C
G
D
H
Zebra Danio
Brachydanio rerio
NP_899185
793
90017
K221
E
G
R
H
W
H
M
K
H
F
S
C
S
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
40
97.1
N.A.
93.1
93.2
N.A.
64.4
87.9
80.7
67.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
50.4
98.8
N.A.
96.5
96.9
N.A.
69.2
93.7
90.2
78.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
93.3
N.A.
0
100
N.A.
93.3
100
80
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
0
100
N.A.
100
100
93.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
80
0
0
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
80
0
10
90
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% D
% Glu:
20
80
0
0
0
10
80
0
10
70
0
0
10
70
0
% E
% Phe:
80
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
10
70
0
0
% G
% His:
0
0
0
20
0
10
0
0
10
0
0
0
0
10
80
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
70
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
80
0
0
0
0
0
0
0
30
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
50
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
80
0
10
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _