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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YTHDC1
All Species:
16.36
Human Site:
S294
Identified Species:
40
UniProt:
Q96MU7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MU7
NP_001026902.1
727
84700
S294
S
G
S
G
T
D
G
S
D
E
K
K
K
E
R
Chimpanzee
Pan troglodytes
XP_517262
727
84680
S294
S
G
S
G
T
D
G
S
D
E
K
K
K
E
R
Rhesus Macaque
Macaca mulatta
XP_001098270
654
76448
G271
L
S
S
E
S
H
H
G
G
S
P
I
H
W
V
Dog
Lupus familis
XP_532391
712
83066
E279
E
A
S
D
S
D
S
E
S
V
S
F
T
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9QY02
738
85807
S297
S
G
S
G
T
D
G
S
D
E
K
K
K
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026318
473
53297
D95
K
G
S
K
R
K
S
D
R
L
E
N
V
E
S
Frog
Xenopus laevis
NP_001088293
704
81861
S273
S
G
S
G
S
D
I
S
D
Q
K
K
K
E
R
Zebra Danio
Brachydanio rerio
NP_001007411
679
78642
S261
S
D
G
E
S
V
H
S
A
S
G
S
D
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395221
545
61700
S167
K
R
A
R
S
R
D
S
K
S
S
S
P
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783255
763
85165
T309
M
R
L
R
V
I
M
T
A
G
R
G
L
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
53.2
95.4
N.A.
N.A.
95.3
N.A.
N.A.
51
72
66.5
N.A.
N.A.
28.3
N.A.
34.6
Protein Similarity:
100
99.7
60.1
96.2
N.A.
N.A.
97
N.A.
N.A.
55.2
83.4
78.2
N.A.
N.A.
41.1
N.A.
50.3
P-Site Identity:
100
100
6.6
13.3
N.A.
N.A.
100
N.A.
N.A.
20
80
13.3
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
13.3
26.6
N.A.
N.A.
100
N.A.
N.A.
26.6
93.3
20
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
20
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
50
10
10
40
0
0
0
10
10
0
% D
% Glu:
10
0
0
20
0
0
0
10
0
30
10
0
0
70
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
50
10
40
0
0
30
10
10
10
10
10
0
0
10
% G
% His:
0
0
0
0
0
10
20
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% I
% Lys:
20
0
0
10
0
10
0
0
10
0
40
40
40
0
0
% K
% Leu:
10
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% L
% Met:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
20
0
20
10
10
0
0
10
0
10
0
0
0
40
% R
% Ser:
50
10
70
0
50
0
20
60
10
30
20
20
0
0
20
% S
% Thr:
0
0
0
0
30
0
0
10
0
0
0
0
10
0
10
% T
% Val:
0
0
0
0
10
10
0
0
0
10
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _