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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YTHDC1 All Species: 14.55
Human Site: S71 Identified Species: 35.56
UniProt: Q96MU7 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96MU7 NP_001026902.1 727 84700 S71 V H S R Q L V S K P L S S S V
Chimpanzee Pan troglodytes XP_517262 727 84680 S71 V H S R Q L V S K P L S S S V
Rhesus Macaque Macaca mulatta XP_001098270 654 76448 Y75 S S A S R E P Y K N Q P E K T
Dog Lupus familis XP_532391 712 83066 S71 V H S R Q L L S K P L S S S V
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q9QY02 738 85807 S71 I H S R Q L I S K P L S S S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026318 473 53297
Frog Xenopus laevis NP_001088293 704 81861 P72 S H M S R Q P P Q R V A S G A
Zebra Danio Brachydanio rerio NP_001007411 679 78642 M71 G H N T R Q P M K R A A P S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395221 545 61700
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783255 763 85165 K88 T S E E P A P K T E T T S E Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 53.2 95.4 N.A. N.A. 95.3 N.A. N.A. 51 72 66.5 N.A. N.A. 28.3 N.A. 34.6
Protein Similarity: 100 99.7 60.1 96.2 N.A. N.A. 97 N.A. N.A. 55.2 83.4 78.2 N.A. N.A. 41.1 N.A. 50.3
P-Site Identity: 100 100 6.6 93.3 N.A. N.A. 86.6 N.A. N.A. 0 13.3 20 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 20 100 N.A. N.A. 100 N.A. N.A. 0 40 40 N.A. N.A. 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 0 0 0 10 20 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 10 0 10 0 0 0 10 0 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 60 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 40 10 0 0 0 40 0 0 0 0 % L
% Met: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 40 10 0 40 0 10 10 0 0 % P
% Gln: 0 0 0 0 40 20 0 0 10 0 10 0 0 0 10 % Q
% Arg: 0 0 0 40 30 0 0 0 0 20 0 0 0 0 0 % R
% Ser: 20 20 40 20 0 0 0 40 0 0 0 40 60 50 10 % S
% Thr: 10 0 0 10 0 0 0 0 10 0 10 10 0 0 10 % T
% Val: 30 0 0 0 0 0 20 0 0 0 10 0 0 0 40 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _