KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YTHDC1
All Species:
20.61
Human Site:
T456
Identified Species:
50.37
UniProt:
Q96MU7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MU7
NP_001026902.1
727
84700
T456
C
R
R
E
L
P
F
T
K
S
A
H
L
T
N
Chimpanzee
Pan troglodytes
XP_517262
727
84680
T456
C
R
R
E
L
P
F
T
K
S
A
H
L
T
N
Rhesus Macaque
Macaca mulatta
XP_001098270
654
76448
D427
D
L
K
C
F
L
E
D
R
H
E
T
L
T
L
Dog
Lupus familis
XP_532391
712
83066
T441
C
R
R
E
L
P
F
T
K
S
A
H
L
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9QY02
738
85807
T459
C
R
R
E
L
P
F
T
K
S
A
H
L
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026318
473
53297
E251
E
E
E
G
M
E
E
E
E
D
D
E
G
E
E
Frog
Xenopus laevis
NP_001088293
704
81861
T435
C
R
R
E
L
S
F
T
K
C
V
H
L
T
N
Zebra Danio
Brachydanio rerio
NP_001007411
679
78642
G418
E
H
K
P
V
K
I
G
R
D
G
Q
E
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395221
545
61700
D323
K
Q
V
K
I
G
R
D
G
Q
E
I
E
P
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783255
763
85165
T471
T
R
N
E
L
P
F
T
K
T
T
H
L
Y
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
53.2
95.4
N.A.
N.A.
95.3
N.A.
N.A.
51
72
66.5
N.A.
N.A.
28.3
N.A.
34.6
Protein Similarity:
100
99.7
60.1
96.2
N.A.
N.A.
97
N.A.
N.A.
55.2
83.4
78.2
N.A.
N.A.
41.1
N.A.
50.3
P-Site Identity:
100
100
13.3
100
N.A.
N.A.
100
N.A.
N.A.
0
80
0
N.A.
N.A.
0
N.A.
66.6
P-Site Similarity:
100
100
26.6
100
N.A.
N.A.
100
N.A.
N.A.
13.3
80
20
N.A.
N.A.
20
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
40
0
0
0
0
% A
% Cys:
50
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
20
0
20
10
0
0
0
0
% D
% Glu:
20
10
10
60
0
10
20
10
10
0
20
10
20
10
20
% E
% Phe:
0
0
0
0
10
0
60
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
10
10
0
10
0
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
10
0
60
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
10
0
10
0
% I
% Lys:
10
0
20
10
0
10
0
0
60
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
60
10
0
0
0
0
0
0
70
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
60
% N
% Pro:
0
0
0
10
0
50
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
60
50
0
0
0
10
0
20
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
10
0
0
0
40
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
60
0
10
10
10
0
60
0
% T
% Val:
0
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _