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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YTHDC1
All Species:
19.39
Human Site:
Y501
Identified Species:
47.41
UniProt:
Q96MU7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MU7
NP_001026902.1
727
84700
Y501
P
D
E
S
I
D
L
Y
Q
V
I
H
K
M
R
Chimpanzee
Pan troglodytes
XP_517262
727
84680
Y501
P
D
E
S
I
D
L
Y
Q
V
I
H
K
M
R
Rhesus Macaque
Macaca mulatta
XP_001098270
654
76448
S464
E
D
Y
D
I
H
N
S
R
K
K
P
R
I
D
Dog
Lupus familis
XP_532391
712
83066
Y486
P
D
E
S
I
D
L
Y
Q
V
I
H
K
M
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9QY02
738
85807
Y504
P
D
E
S
I
D
L
Y
Q
L
I
H
K
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026318
473
53297
D287
Q
K
E
G
N
D
Y
D
T
R
S
E
A
S
D
Frog
Xenopus laevis
NP_001088293
704
81861
Y480
A
D
D
S
I
D
L
Y
Q
V
I
H
K
M
R
Zebra Danio
Brachydanio rerio
NP_001007411
679
78642
R455
I
H
K
M
R
H
K
R
R
M
H
S
E
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395221
545
61700
K359
R
K
S
K
E
A
A
K
H
I
T
K
S
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783255
763
85165
V516
R
D
E
N
I
D
V
V
E
I
L
R
A
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
53.2
95.4
N.A.
N.A.
95.3
N.A.
N.A.
51
72
66.5
N.A.
N.A.
28.3
N.A.
34.6
Protein Similarity:
100
99.7
60.1
96.2
N.A.
N.A.
97
N.A.
N.A.
55.2
83.4
78.2
N.A.
N.A.
41.1
N.A.
50.3
P-Site Identity:
100
100
13.3
100
N.A.
N.A.
93.3
N.A.
N.A.
13.3
86.6
6.6
N.A.
N.A.
0
N.A.
33.3
P-Site Similarity:
100
100
33.3
100
N.A.
N.A.
100
N.A.
N.A.
13.3
93.3
33.3
N.A.
N.A.
6.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
10
0
0
0
0
0
20
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
10
10
0
70
0
10
0
0
0
0
0
0
20
% D
% Glu:
10
0
60
0
10
0
0
0
10
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
20
0
0
10
0
10
50
0
0
0
% H
% Ile:
10
0
0
0
70
0
0
0
0
20
50
0
0
10
0
% I
% Lys:
0
20
10
10
0
0
10
10
0
10
10
10
50
0
0
% K
% Leu:
0
0
0
0
0
0
50
0
0
10
10
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
10
0
0
0
50
0
% M
% Asn:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
40
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
10
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% Q
% Arg:
20
0
0
0
10
0
0
10
20
10
0
10
10
10
70
% R
% Ser:
0
0
10
50
0
0
0
10
0
0
10
10
10
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
10
0
40
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
10
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _