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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YTHDC1
All Species:
14.24
Human Site:
Y563
Identified Species:
34.81
UniProt:
Q96MU7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MU7
NP_001026902.1
727
84700
Y563
E
F
H
Q
R
P
G
Y
L
K
D
P
R
Y
Q
Chimpanzee
Pan troglodytes
XP_517262
727
84680
Y563
E
F
H
Q
R
P
G
Y
L
K
D
P
R
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001098270
654
76448
N525
D
Y
V
R
E
F
H
N
M
G
P
P
P
P
W
Dog
Lupus familis
XP_532391
712
83066
Y548
E
F
H
Q
R
P
G
Y
L
K
D
P
R
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9QY02
738
85807
Y566
E
F
H
Q
R
P
G
Y
L
K
D
P
R
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026318
473
53297
S348
A
S
E
S
Y
A
G
S
E
K
K
H
E
K
L
Frog
Xenopus laevis
NP_001088293
704
81861
F541
E
F
H
Q
R
P
G
F
V
K
D
P
R
Y
Q
Zebra Danio
Brachydanio rerio
NP_001007411
679
78642
F520
N
P
P
V
D
R
R
F
S
G
V
R
R
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395221
545
61700
H420
R
G
S
R
D
H
H
H
H
R
Y
A
T
W
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783255
763
85165
R578
Q
P
S
R
D
D
R
R
R
M
R
P
P
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
53.2
95.4
N.A.
N.A.
95.3
N.A.
N.A.
51
72
66.5
N.A.
N.A.
28.3
N.A.
34.6
Protein Similarity:
100
99.7
60.1
96.2
N.A.
N.A.
97
N.A.
N.A.
55.2
83.4
78.2
N.A.
N.A.
41.1
N.A.
50.3
P-Site Identity:
100
100
6.6
100
N.A.
N.A.
100
N.A.
N.A.
13.3
86.6
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
N.A.
100
N.A.
N.A.
13.3
100
13.3
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
30
10
0
0
0
0
50
0
0
10
0
% D
% Glu:
50
0
10
0
10
0
0
0
10
0
0
0
10
0
0
% E
% Phe:
0
50
0
0
0
10
0
20
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
0
0
0
60
0
0
20
0
0
0
0
0
% G
% His:
0
0
50
0
0
10
20
10
10
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
60
10
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
20
10
0
0
50
0
0
0
0
10
70
20
20
0
% P
% Gln:
10
0
0
50
0
0
0
0
0
0
0
0
0
0
50
% Q
% Arg:
10
0
0
30
50
10
20
10
10
10
10
10
60
0
0
% R
% Ser:
0
10
20
10
0
0
0
10
10
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
10
10
0
0
0
0
10
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% W
% Tyr:
0
10
0
0
10
0
0
40
0
0
10
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _