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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KREMEN1
All Species:
12.73
Human Site:
S425
Identified Species:
31.11
UniProt:
Q96MU8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MU8
NP_001034659.2
473
51744
S425
K
S
H
R
V
P
A
S
G
D
L
R
D
C
H
Chimpanzee
Pan troglodytes
XP_001172958
475
51894
S427
K
S
H
R
V
P
A
S
G
D
L
R
D
C
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543466
458
50186
G411
S
H
R
V
P
A
S
G
D
L
R
D
C
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99N43
473
51698
S425
K
S
H
R
V
P
A
S
G
D
L
R
D
C
R
Rat
Rattus norvegicus
Q924S4
473
51851
S425
K
S
H
R
V
T
A
S
G
D
L
R
D
C
R
Wallaby
Macropus eugenll
O18783
806
90963
P679
A
I
N
D
K
V
I
P
A
C
L
P
S
Q
D
Platypus
Ornith. anatinus
XP_001517970
615
65703
N501
P
V
P
P
E
G
A
N
G
S
R
A
P
G
P
Chicken
Gallus gallus
XP_415211
452
50370
P405
M
R
S
H
Q
I
P
P
A
N
E
T
E
D
P
Frog
Xenopus laevis
Q90Y90
452
50170
A405
S
M
K
S
A
R
L
A
S
S
S
S
L
D
S
Zebra Danio
Brachydanio rerio
Q7SXB3
263
28758
L216
M
H
R
I
T
L
P
L
S
A
F
A
N
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
93.2
N.A.
93
92.8
21.2
30.2
69.5
67.8
22.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
N.A.
94.7
N.A.
96.1
96.4
30.5
42.7
81.4
78.2
31.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
0
N.A.
93.3
86.6
6.6
13.3
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
6.6
N.A.
93.3
86.6
13.3
20
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
10
50
10
20
10
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
10
40
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
40
0
10
40
20
10
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
10
50
0
0
0
0
10
0
% G
% His:
0
20
40
10
0
0
0
0
0
0
0
0
0
10
20
% H
% Ile:
0
10
0
10
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
40
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
10
10
0
10
50
0
10
0
0
% L
% Met:
20
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
0
10
0
0
10
0
0
% N
% Pro:
10
0
10
10
10
30
20
20
0
0
0
10
10
10
20
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
0
10
20
40
0
10
0
0
0
0
20
40
0
0
20
% R
% Ser:
20
40
10
10
0
0
10
40
20
20
10
10
10
0
10
% S
% Thr:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
10
% T
% Val:
0
10
0
10
40
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _