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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM56 All Species: 31.82
Human Site: S152 Identified Species: 58.33
UniProt: Q96MV1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96MV1 NP_689700.1 263 30041 S152 R L L A E L S S P F V N Q R W
Chimpanzee Pan troglodytes XP_524620 263 30010 S152 R L L A E L S S P F V N Q R W
Rhesus Macaque Macaca mulatta XP_001103909 263 30144 S152 R L L A E L S S P F V N Q R W
Dog Lupus familis XP_547272 263 30212 S152 R L L A E L S S P F V N Q R W
Cat Felis silvestris
Mouse Mus musculus Q8CGF5 276 31217 S165 R L L A E L S S P F V N Q R W
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518543 135 15202 T25 R L L A E F S T P F V N Q R W
Chicken Gallus gallus
Frog Xenopus laevis Q6PGS5 262 29834 T152 R L I A E F S T P F V N Q R W
Zebra Danio Brachydanio rerio Q5XIY2 264 29909 N153 E L S T P F V N Q R W F F E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203034 276 31599 T161 R V N A E F S T P F V N L R W
Poplar Tree Populus trichocarpa XP_002325620 265 29872 Q155 A L L S G Q A Q I Y I L M V L
Maize Zea mays NP_001149791 268 30861 T154 S L V A I A Y T M L S G E G Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567355 266 30189 Q152 S V T S G Q S Q F Y I F L V L
Baker's Yeast Sacchar. cerevisiae P47153 279 31993 I169 P W I G R F L I Y E A S T P F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.4 80.6 N.A. 73.5 N.A. N.A. 35.7 N.A. 54.3 47.3 N.A. N.A. N.A. N.A. 30.8
Protein Similarity: 100 99.6 97.3 88.9 N.A. 82.6 N.A. N.A. 41.4 N.A. 72.2 67 N.A. N.A. N.A. N.A. 51.8
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 86.6 N.A. 80 6.6 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 N.A. 93.3 13.3 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: 28.6 28.7 N.A. 26.6 25.4 N.A.
Protein Similarity: 51.3 51.1 N.A. 49.6 48.3 N.A.
P-Site Identity: 13.3 13.3 N.A. 6.6 0 N.A.
P-Site Similarity: 40 33.3 N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 70 0 8 8 0 0 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 62 0 0 0 0 8 0 0 8 8 0 % E
% Phe: 0 0 0 0 0 39 0 0 8 62 0 16 8 0 8 % F
% Gly: 0 0 0 8 16 0 0 0 0 0 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 16 0 8 0 0 8 8 0 16 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 77 54 0 0 39 8 0 0 8 0 8 16 0 16 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % M
% Asn: 0 0 8 0 0 0 0 8 0 0 0 62 0 0 0 % N
% Pro: 8 0 0 0 8 0 0 0 62 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 16 0 16 8 0 0 0 54 0 8 % Q
% Arg: 62 0 0 0 8 0 0 0 0 8 0 0 0 62 0 % R
% Ser: 16 0 8 16 0 0 70 39 0 0 8 8 0 0 0 % S
% Thr: 0 0 8 8 0 0 0 31 0 0 0 0 8 0 0 % T
% Val: 0 16 8 0 0 0 8 0 0 0 62 0 0 16 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 62 % W
% Tyr: 0 0 0 0 0 0 8 0 8 16 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _