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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM56
All Species:
23.33
Human Site:
S35
Identified Species:
42.78
UniProt:
Q96MV1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MV1
NP_689700.1
263
30041
S35
Y
W
F
S
A
K
V
S
P
G
F
N
S
L
S
Chimpanzee
Pan troglodytes
XP_524620
263
30010
S35
Y
W
F
S
A
K
V
S
P
G
F
N
S
L
S
Rhesus Macaque
Macaca mulatta
XP_001103909
263
30144
S35
Y
W
F
S
A
K
V
S
P
G
F
N
S
L
S
Dog
Lupus familis
XP_547272
263
30212
S35
F
W
F
S
A
K
V
S
P
G
F
V
S
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGF5
276
31217
S48
Y
W
F
S
A
R
V
S
S
G
Y
N
S
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518543
135
15202
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PGS5
262
29834
T35
S
W
L
S
T
R
L
T
G
G
F
H
K
L
S
Zebra Danio
Brachydanio rerio
Q5XIY2
264
29909
K37
N
F
T
Q
G
Y
G
K
L
P
P
N
K
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203034
276
31599
V44
P
Y
L
S
W
W
L
V
P
K
Y
R
T
I
S
Poplar Tree
Populus trichocarpa
XP_002325620
265
29872
T38
C
G
I
V
Y
K
L
T
A
F
V
S
R
L
Y
Maize
Zea mays
NP_001149791
268
30861
I36
Y
T
S
V
L
F
G
I
V
L
C
K
A
Y
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567355
266
30189
T35
C
K
I
V
Y
D
L
T
R
F
I
S
P
L
L
Baker's Yeast
Sacchar. cerevisiae
P47153
279
31993
A51
Q
L
A
F
S
V
V
A
P
F
L
N
K
V
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.4
80.6
N.A.
73.5
N.A.
N.A.
35.7
N.A.
54.3
47.3
N.A.
N.A.
N.A.
N.A.
30.8
Protein Similarity:
100
99.6
97.3
88.9
N.A.
82.6
N.A.
N.A.
41.4
N.A.
72.2
67
N.A.
N.A.
N.A.
N.A.
51.8
P-Site Identity:
100
100
100
86.6
N.A.
80
N.A.
N.A.
0
N.A.
40
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
0
N.A.
66.6
26.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
28.6
28.7
N.A.
26.6
25.4
N.A.
Protein Similarity:
51.3
51.1
N.A.
49.6
48.3
N.A.
P-Site Identity:
13.3
6.6
N.A.
6.6
20
N.A.
P-Site Similarity:
33.3
13.3
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
39
0
0
8
8
0
0
0
8
0
0
% A
% Cys:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
39
8
0
8
0
0
0
24
39
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
16
0
8
47
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
8
0
0
8
0
0
8
0
% I
% Lys:
0
8
0
0
0
39
0
8
0
8
0
8
24
0
0
% K
% Leu:
0
8
16
0
8
0
31
0
8
8
8
0
0
70
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
47
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
47
8
8
0
8
0
0
% P
% Gln:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
16
0
0
8
0
0
8
8
0
0
% R
% Ser:
8
0
8
54
8
0
0
39
8
0
0
16
39
0
54
% S
% Thr:
0
8
8
0
8
0
0
24
0
0
0
0
8
0
0
% T
% Val:
0
0
0
24
0
8
47
8
8
0
8
8
0
8
8
% V
% Trp:
0
47
0
0
8
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
39
8
0
0
16
8
0
0
0
0
16
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _