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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM56
All Species:
25.15
Human Site:
S42
Identified Species:
46.11
UniProt:
Q96MV1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MV1
NP_689700.1
263
30041
S42
S
P
G
F
N
S
L
S
F
K
K
K
I
E
W
Chimpanzee
Pan troglodytes
XP_524620
263
30010
S42
S
P
G
F
N
S
L
S
F
K
K
K
I
E
W
Rhesus Macaque
Macaca mulatta
XP_001103909
263
30144
S42
S
P
G
F
N
S
L
S
F
E
K
K
I
E
W
Dog
Lupus familis
XP_547272
263
30212
S42
S
P
G
F
V
S
L
S
F
E
K
K
I
E
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGF5
276
31217
S55
S
S
G
Y
N
S
L
S
I
D
K
K
I
E
W
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518543
135
15202
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PGS5
262
29834
S42
T
G
G
F
H
K
L
S
A
R
Q
K
I
E
W
Zebra Danio
Brachydanio rerio
Q5XIY2
264
29909
N44
K
L
P
P
N
K
L
N
D
W
N
S
R
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203034
276
31599
S51
V
P
K
Y
R
T
I
S
T
P
E
R
F
D
W
Poplar Tree
Populus trichocarpa
XP_002325620
265
29872
Y45
T
A
F
V
S
R
L
Y
F
K
G
Y
G
K
L
Maize
Zea mays
NP_001149791
268
30861
D43
I
V
L
C
K
A
Y
D
F
T
R
I
L
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567355
266
30189
L42
T
R
F
I
S
P
L
L
F
S
V
Y
G
K
L
Baker's Yeast
Sacchar. cerevisiae
P47153
279
31993
V58
A
P
F
L
N
K
V
V
F
R
K
H
Y
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.4
80.6
N.A.
73.5
N.A.
N.A.
35.7
N.A.
54.3
47.3
N.A.
N.A.
N.A.
N.A.
30.8
Protein Similarity:
100
99.6
97.3
88.9
N.A.
82.6
N.A.
N.A.
41.4
N.A.
72.2
67
N.A.
N.A.
N.A.
N.A.
51.8
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
N.A.
N.A.
0
N.A.
53.3
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
80
N.A.
N.A.
0
N.A.
80
20
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
28.6
28.7
N.A.
26.6
25.4
N.A.
Protein Similarity:
51.3
51.1
N.A.
49.6
48.3
N.A.
P-Site Identity:
20
6.6
N.A.
13.3
26.6
N.A.
P-Site Similarity:
40
26.6
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
8
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
16
8
0
0
47
0
% E
% Phe:
0
0
24
39
0
0
0
0
62
0
0
0
8
0
0
% F
% Gly:
0
8
47
0
0
0
0
0
0
0
8
0
16
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
8
0
0
8
0
8
0
0
8
47
0
0
% I
% Lys:
8
0
8
0
8
24
0
0
0
24
47
47
0
16
0
% K
% Leu:
0
8
8
8
0
0
70
8
0
0
0
0
8
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
47
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
47
8
8
0
8
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
8
8
0
0
0
16
8
8
8
0
0
% R
% Ser:
39
8
0
0
16
39
0
54
0
8
0
8
0
8
8
% S
% Thr:
24
0
0
0
0
8
0
0
8
8
0
0
0
8
8
% T
% Val:
8
8
0
8
8
0
8
8
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
54
% W
% Tyr:
0
0
0
16
0
0
8
8
0
0
0
16
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _