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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM56 All Species: 15.15
Human Site: Y203 Identified Species: 27.78
UniProt: Q96MV1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96MV1 NP_689700.1 263 30041 Y203 Y G F M Y S V Y G T E P Y I R
Chimpanzee Pan troglodytes XP_524620 263 30010 Y203 Y G F M Y S V Y G T E P Y I R
Rhesus Macaque Macaca mulatta XP_001103909 263 30144 Y203 Y G F M Y S V Y G T E P Y K R
Dog Lupus familis XP_547272 263 30212 L203 Y S Y M Y S V L G T E A Y I R
Cat Felis silvestris
Mouse Mus musculus Q8CGF5 276 31217 Y216 Y F F L Y S V Y G T E P Y I R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518543 135 15202 F76 Y G Y I L A A F G T E A Y N R
Chicken Gallus gallus
Frog Xenopus laevis Q6PGS5 262 29834 F203 Y G R V F S T F G T E A F H R
Zebra Danio Brachydanio rerio Q5XIY2 264 29909 T204 F G I I Y S P T F E K L G L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203034 276 31599 F212 Y F M L K S F F E K G F R R L
Poplar Tree Populus trichocarpa XP_002325620 265 29872 L206 W L V A R I L L F I F F F S H
Maize Zea mays NP_001149791 268 30861 W205 G I L M F V A W L V A R I F L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567355 266 30189 L203 W L V A R V L L F I F F F V H
Baker's Yeast Sacchar. cerevisiae P47153 279 31993 I220 V R I C W G S I A S A L L F R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.4 80.6 N.A. 73.5 N.A. N.A. 35.7 N.A. 54.3 47.3 N.A. N.A. N.A. N.A. 30.8
Protein Similarity: 100 99.6 97.3 88.9 N.A. 82.6 N.A. N.A. 41.4 N.A. 72.2 67 N.A. N.A. N.A. N.A. 51.8
P-Site Identity: 100 100 93.3 73.3 N.A. 86.6 N.A. N.A. 46.6 N.A. 46.6 20 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 80 N.A. 93.3 N.A. N.A. 73.3 N.A. 73.3 46.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 28.6 28.7 N.A. 26.6 25.4 N.A.
Protein Similarity: 51.3 51.1 N.A. 49.6 48.3 N.A.
P-Site Identity: 0 6.6 N.A. 0 6.6 N.A.
P-Site Similarity: 20 20 N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 8 16 0 8 0 16 24 0 0 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 8 54 0 0 0 0 % E
% Phe: 8 16 31 0 16 0 8 24 24 0 16 24 24 16 0 % F
% Gly: 8 47 0 0 0 8 0 0 54 0 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 16 % H
% Ile: 0 8 16 16 0 8 0 8 0 16 0 0 8 31 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 8 8 0 0 8 0 % K
% Leu: 0 16 8 16 8 0 16 24 8 0 0 16 8 8 16 % L
% Met: 0 0 8 39 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 0 31 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 8 0 16 0 0 0 0 0 0 8 8 8 62 % R
% Ser: 0 8 0 0 0 62 8 0 0 8 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 8 8 0 54 0 0 0 0 0 % T
% Val: 8 0 16 8 0 16 39 0 0 8 0 0 0 8 0 % V
% Trp: 16 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 62 0 16 0 47 0 0 31 0 0 0 0 47 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _