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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG8
All Species:
22.12
Human Site:
S488
Identified Species:
37.44
UniProt:
Q96MW5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MW5
NP_115758.3
612
68424
S488
R
A
E
E
A
A
F
S
S
G
E
Q
E
L
F
Chimpanzee
Pan troglodytes
XP_511064
394
44531
L295
V
L
L
D
F
P
P
L
A
C
F
L
N
N
I
Rhesus Macaque
Macaca mulatta
XP_001100394
487
54500
C388
L
V
P
Y
L
N
R
C
L
Q
V
L
F
P
P
Dog
Lupus familis
XP_546857
624
69140
S490
R
A
E
E
A
A
F
S
T
G
E
Q
E
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA2
640
71600
S494
R
A
E
E
A
V
F
S
S
G
E
H
E
I
F
Rat
Rattus norvegicus
NP_001099652
634
70744
S494
R
A
E
E
A
V
F
S
S
G
E
H
E
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510195
500
55836
Q400
Q
V
L
F
P
P
A
Q
I
A
Q
T
L
G
I
Chicken
Gallus gallus
XP_001232975
677
74631
S464
R
A
E
E
A
A
F
S
G
R
E
Q
E
L
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013524
634
71570
S469
R
A
E
E
S
A
F
S
S
R
E
R
E
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKH0
570
64891
L465
Q
Q
A
A
Q
R
V
L
A
F
Y
R
Q
E
Q
Honey Bee
Apis mellifera
XP_623492
605
69076
A456
K
Q
E
Q
Q
A
F
A
A
P
E
R
E
N
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204069
378
43256
W279
E
A
A
L
F
Q
G
W
V
V
E
K
V
S
Q
Poplar Tree
Populus trichocarpa
XP_002308543
575
64166
Y476
R
S
F
I
E
V
A
Y
P
H
C
A
T
C
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568256
569
63034
S466
S
E
S
N
L
F
L
S
L
C
R
A
F
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
76.9
86.5
N.A.
86
87.6
N.A.
65.3
63.2
N.A.
67
N.A.
41.5
40.6
N.A.
41.1
Protein Similarity:
100
64.2
77.7
90.3
N.A.
89
91
N.A.
70.7
71.7
N.A.
78.7
N.A.
59.1
62
N.A.
51.1
P-Site Identity:
100
0
0
93.3
N.A.
80
80
N.A.
0
86.6
N.A.
80
N.A.
0
33.3
N.A.
13.3
P-Site Similarity:
100
13.3
0
100
N.A.
86.6
86.6
N.A.
13.3
86.6
N.A.
93.3
N.A.
26.6
66.6
N.A.
20
Percent
Protein Identity:
32.3
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
49.6
N.A.
N.A.
49.6
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
15
8
36
36
15
8
22
8
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
15
8
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
50
43
8
0
0
0
0
0
58
0
50
8
8
% E
% Phe:
0
0
8
8
15
8
50
0
0
8
8
0
15
0
50
% F
% Gly:
0
0
0
0
0
0
8
0
8
29
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
15
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
0
15
15
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
8
15
8
15
0
8
15
15
0
0
15
8
29
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
0
0
8
15
0
% N
% Pro:
0
0
8
0
8
15
8
0
8
8
0
0
0
8
8
% P
% Gln:
15
15
0
8
15
8
0
8
0
8
8
22
8
0
15
% Q
% Arg:
50
0
0
0
0
8
8
0
0
15
8
22
0
0
0
% R
% Ser:
8
8
8
0
8
0
0
50
29
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
8
8
0
0
% T
% Val:
8
15
0
0
0
22
8
0
8
8
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _