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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF578
All Species:
12.73
Human Site:
Y286
Identified Species:
70
UniProt:
Q96N58
Number Species:
4
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96N58
NP_001093164.1
365
42597
Y286
L
H
S
G
E
K
P
Y
K
C
N
E
C
G
K
Chimpanzee
Pan troglodytes
XP_513016
337
39528
K259
H
S
G
E
K
P
Y
K
C
N
E
C
G
K
T
Rhesus Macaque
Macaca mulatta
XP_001115888
843
98618
Y534
R
H
T
G
E
K
P
Y
K
C
N
D
C
G
K
Dog
Lupus familis
XP_539392
780
90887
Y701
I
H
T
G
E
K
P
Y
K
C
K
E
C
A
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_663458
650
73427
Y482
I
H
T
G
E
K
P
Y
R
C
N
E
C
G
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
30.3
29.7
N.A.
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.9
35.4
38.2
N.A.
44.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
80
73.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
93.3
86.6
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
20
80
0
20
80
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% D
% Glu:
0
0
0
20
80
0
0
0
0
0
20
60
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
80
0
0
0
0
0
0
0
0
20
60
0
% G
% His:
20
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
20
80
0
20
60
0
20
0
0
20
80
% K
% Leu:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
20
60
0
0
0
0
% N
% Pro:
0
0
0
0
0
20
80
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% R
% Ser:
0
20
20
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
20
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _