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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWWP2A
All Species:
3.64
Human Site:
S244
Identified Species:
10
UniProt:
Q96N64
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96N64
NP_001124336.1
755
81960
S244
G
A
V
P
D
D
P
S
P
V
P
H
P
E
L
Chimpanzee
Pan troglodytes
XP_527102
538
59830
P46
S
L
W
T
S
K
P
P
P
L
F
H
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001092260
513
55832
G21
V
Q
P
P
E
T
T
G
P
E
P
P
P
P
L
Dog
Lupus familis
XP_853285
538
59617
P46
S
L
W
T
S
K
P
P
P
L
F
H
E
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z61
730
79369
S224
G
A
V
P
D
D
L
S
P
V
P
P
P
E
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506246
617
69027
P125
L
W
T
S
K
P
P
P
L
F
H
E
G
A
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687488
955
103666
N397
S
T
P
Q
P
C
P
N
P
Q
P
N
P
W
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395213
680
75929
K188
N
A
L
Q
A
N
E
K
V
K
I
S
P
S
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796495
568
61717
I74
K
E
F
G
V
P
V
I
D
T
A
F
I
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.1
28.4
69
N.A.
85.3
N.A.
N.A.
71.1
N.A.
N.A.
48.6
N.A.
N.A.
20.7
N.A.
24.5
Protein Similarity:
100
71.2
43.8
70.4
N.A.
89.6
N.A.
N.A.
77.4
N.A.
N.A.
60
N.A.
N.A.
37.6
N.A.
38.6
P-Site Identity:
100
20
33.3
20
N.A.
80
N.A.
N.A.
6.6
N.A.
N.A.
26.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
26.6
40
26.6
N.A.
80
N.A.
N.A.
6.6
N.A.
N.A.
40
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
12
0
0
0
0
0
12
0
0
12
23
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
23
23
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
12
0
12
0
0
12
0
12
23
23
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
12
23
12
0
0
0
% F
% Gly:
23
0
0
12
0
0
0
12
0
0
0
0
12
23
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
34
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
12
0
12
0
0
% I
% Lys:
12
0
0
0
12
23
0
12
0
12
0
0
0
12
0
% K
% Leu:
12
23
12
0
0
0
12
0
12
23
0
0
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
12
0
12
0
0
0
12
0
0
0
% N
% Pro:
0
0
23
34
12
23
56
34
67
0
45
23
56
12
12
% P
% Gln:
0
12
0
23
0
0
0
0
0
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
34
0
0
12
23
0
0
23
0
0
0
12
0
12
0
% S
% Thr:
0
12
12
23
0
12
12
0
0
12
0
0
0
0
12
% T
% Val:
12
0
23
0
12
0
12
0
12
23
0
0
0
0
0
% V
% Trp:
0
12
23
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _