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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PWWP2A All Species: 5.76
Human Site: S499 Identified Species: 15.83
UniProt: Q96N64 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96N64 NP_001124336.1 755 81960 S499 T G L E K M R S G K M A P K P
Chimpanzee Pan troglodytes XP_527102 538 59830 G283 G L E K M R S G K M A P K P Q
Rhesus Macaque Macaca mulatta XP_001092260 513 55832 L258 L P P P K I R L K P H R L G D
Dog Lupus familis XP_853285 538 59617 G283 G L E K M R S G K M A P K P Q
Cat Felis silvestris
Mouse Mus musculus Q69Z61 730 79369 S472 T G L E K I R S G K L A P K P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506246 617 69027 G362 G L E K L R S G K M A A K P Q
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687488 955 103666 A699 S C S A S Q V A T A V E P Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395213 680 75929 Y425 P T Y D T L S Y H R R K H K V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796495 568 61717 H311 K A P V N T Q H D K I R I V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.1 28.4 69 N.A. 85.3 N.A. N.A. 71.1 N.A. N.A. 48.6 N.A. N.A. 20.7 N.A. 24.5
Protein Similarity: 100 71.2 43.8 70.4 N.A. 89.6 N.A. N.A. 77.4 N.A. N.A. 60 N.A. N.A. 37.6 N.A. 38.6
P-Site Identity: 100 0 13.3 0 N.A. 86.6 N.A. N.A. 6.6 N.A. N.A. 6.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 6.6 20 6.6 N.A. 100 N.A. N.A. 13.3 N.A. N.A. 33.3 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 12 0 0 0 12 0 12 34 34 0 0 0 % A
% Cys: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 0 0 0 12 0 0 0 0 0 12 % D
% Glu: 0 0 34 23 0 0 0 0 0 0 0 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 23 0 0 0 0 0 34 23 0 0 0 0 12 0 % G
% His: 0 0 0 0 0 0 0 12 12 0 12 0 12 0 0 % H
% Ile: 0 0 0 0 0 23 0 0 0 0 12 0 12 0 0 % I
% Lys: 12 0 0 34 34 0 0 0 45 34 0 12 34 34 12 % K
% Leu: 12 34 23 0 12 12 0 12 0 0 12 0 12 0 0 % L
% Met: 0 0 0 0 23 12 0 0 0 34 12 0 0 0 0 % M
% Asn: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 12 23 12 0 0 0 0 0 12 0 23 34 34 23 % P
% Gln: 0 0 0 0 0 12 12 0 0 0 0 0 0 12 34 % Q
% Arg: 0 0 0 0 0 34 34 0 0 12 12 23 0 0 12 % R
% Ser: 12 0 12 0 12 0 45 23 0 0 0 0 0 0 0 % S
% Thr: 23 12 0 0 12 12 0 0 12 0 0 0 0 0 0 % T
% Val: 0 0 0 12 0 0 12 0 0 0 12 0 0 12 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 12 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _