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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWWP2A
All Species:
17.27
Human Site:
S621
Identified Species:
47.5
UniProt:
Q96N64
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96N64
NP_001124336.1
755
81960
S621
P
S
T
S
S
T
S
S
S
S
K
E
E
K
K
Chimpanzee
Pan troglodytes
XP_527102
538
59830
S405
S
T
S
S
T
S
S
S
S
K
E
E
K
K
L
Rhesus Macaque
Macaca mulatta
XP_001092260
513
55832
E380
H
G
A
S
A
P
S
E
S
R
E
A
R
Q
T
Dog
Lupus familis
XP_853285
538
59617
S405
S
T
S
S
T
S
S
S
S
K
E
E
K
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z61
730
79369
T594
P
S
A
S
S
T
S
T
S
F
S
S
K
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506246
617
69027
S484
S
T
S
S
T
S
S
S
S
K
E
E
K
K
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687488
955
103666
S821
A
F
A
S
A
S
P
S
A
P
Q
D
D
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395213
680
75929
P547
D
F
P
P
Q
S
H
P
L
M
M
R
L
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796495
568
61717
A433
S
D
A
S
S
T
V
A
P
K
K
K
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.1
28.4
69
N.A.
85.3
N.A.
N.A.
71.1
N.A.
N.A.
48.6
N.A.
N.A.
20.7
N.A.
24.5
Protein Similarity:
100
71.2
43.8
70.4
N.A.
89.6
N.A.
N.A.
77.4
N.A.
N.A.
60
N.A.
N.A.
37.6
N.A.
38.6
P-Site Identity:
100
40
20
40
N.A.
46.6
N.A.
N.A.
40
N.A.
N.A.
26.6
N.A.
N.A.
0
N.A.
33.3
P-Site Similarity:
100
80
40
80
N.A.
73.3
N.A.
N.A.
80
N.A.
N.A.
66.6
N.A.
N.A.
6.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
45
0
23
0
0
12
12
0
0
12
0
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
0
0
0
0
0
0
0
0
12
12
0
0
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
45
45
23
23
23
% E
% Phe:
0
23
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
45
23
12
45
56
23
% K
% Leu:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
23
0
12
12
0
12
12
12
12
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
12
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
12
12
0
0
% R
% Ser:
45
23
34
89
34
56
67
56
67
12
12
12
0
0
0
% S
% Thr:
0
34
12
0
34
34
0
12
0
0
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _