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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PWWP2A All Species: 6.36
Human Site: S694 Identified Species: 17.5
UniProt: Q96N64 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96N64 NP_001124336.1 755 81960 S694 V R Q E A R I S W F G S P T T
Chimpanzee Pan troglodytes XP_527102 538 59830 W478 R Q E A R I S W F G S P T T S
Rhesus Macaque Macaca mulatta XP_001092260 513 55832 W453 W R E A K V S W F G S P T T S
Dog Lupus familis XP_853285 538 59617 W478 R Q E A R I S W F G S P T T S
Cat Felis silvestris
Mouse Mus musculus Q69Z61 730 79369 R667 L L A R Q E A R I S W F A S P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506246 617 69027 W557 R Q E A R I S W F G S P T T S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687488 955 103666 S894 V R Q E A R V S W F G S P T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395213 680 75929 S620 S S T S S L M S C D Q L S P F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796495 568 61717 S506 A Q I T W F A S R S I S F M P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.1 28.4 69 N.A. 85.3 N.A. N.A. 71.1 N.A. N.A. 48.6 N.A. N.A. 20.7 N.A. 24.5
Protein Similarity: 100 71.2 43.8 70.4 N.A. 89.6 N.A. N.A. 77.4 N.A. N.A. 60 N.A. N.A. 37.6 N.A. 38.6
P-Site Identity: 100 6.6 13.3 6.6 N.A. 0 N.A. N.A. 6.6 N.A. N.A. 93.3 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 33.3 33.3 33.3 N.A. 13.3 N.A. N.A. 33.3 N.A. N.A. 100 N.A. N.A. 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 45 23 0 23 0 0 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % D
% Glu: 0 0 45 23 0 12 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 12 0 0 45 23 0 12 12 0 12 % F
% Gly: 0 0 0 0 0 0 0 0 0 45 23 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 34 12 0 12 0 12 0 0 0 0 % I
% Lys: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 12 0 0 0 12 0 0 0 0 0 12 0 0 0 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 45 23 12 23 % P
% Gln: 0 45 23 0 12 0 0 0 0 0 12 0 0 0 0 % Q
% Arg: 34 34 0 12 34 23 0 12 12 0 0 0 0 0 0 % R
% Ser: 12 12 0 12 12 0 45 45 0 23 45 34 12 12 45 % S
% Thr: 0 0 12 12 0 0 0 0 0 0 0 0 45 67 23 % T
% Val: 23 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % V
% Trp: 12 0 0 0 12 0 0 45 23 0 12 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _