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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSNARE1
All Species:
14.24
Human Site:
S274
Identified Species:
28.48
UniProt:
Q96NA8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NA8
NP_659440.2
513
55949
S274
N
V
F
R
I
N
S
S
V
T
S
L
E
R
S
Chimpanzee
Pan troglodytes
XP_519987
827
88732
S274
N
V
F
R
I
N
S
S
V
T
S
L
E
R
S
Rhesus Macaque
Macaca mulatta
XP_001089591
511
55788
S274
N
V
F
R
I
N
S
S
V
T
S
L
E
R
S
Dog
Lupus familis
XP_539185
510
54763
S270
S
V
F
Q
I
N
S
S
V
S
S
L
E
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER00
274
31177
M47
T
A
Q
I
K
N
L
M
S
Q
L
G
T
K
Q
Rat
Rattus norvegicus
O70257
261
29832
Q33
T
Q
C
S
A
E
I
Q
R
T
L
N
Q
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518833
249
28356
M22
A
A
Q
I
K
N
L
M
S
Q
L
G
T
K
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079671
259
29246
R32
Q
S
S
S
E
I
Q
R
I
V
V
H
Q
L
G
Zebra Danio
Brachydanio rerio
XP_697581
267
30970
K40
T
Q
N
T
G
Q
I
K
S
M
L
F
Q
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623620
281
32229
S54
P
T
E
L
Y
S
L
S
E
N
I
T
T
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39233
279
31043
R52
T
A
V
N
S
F
F
R
L
V
N
S
I
G
T
Baker's Yeast
Sacchar. cerevisiae
P32854
288
32988
R60
T
L
K
S
F
I
D
R
G
D
V
S
A
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
95.7
79.9
N.A.
22.8
20
N.A.
21.8
N.A.
23
22
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
100
61.4
96.4
86.1
N.A.
37.8
33.5
N.A.
34.1
N.A.
33.7
35.4
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
6.6
6.6
N.A.
6.6
N.A.
0
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
13.3
N.A.
13.3
6.6
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
0
0
9
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
9
0
9
9
0
0
9
0
0
0
34
0
0
% E
% Phe:
0
0
34
0
9
9
9
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
9
0
0
17
0
9
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
17
34
17
17
0
9
0
9
0
9
0
9
% I
% Lys:
0
0
9
0
17
0
0
9
0
0
0
0
0
25
0
% K
% Leu:
0
9
0
9
0
0
25
0
9
0
34
34
0
25
0
% L
% Met:
0
0
0
0
0
0
0
17
0
9
0
0
0
0
0
% M
% Asn:
25
0
9
9
0
50
0
0
0
9
9
9
0
9
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
17
17
9
0
9
9
9
0
17
0
0
25
9
17
% Q
% Arg:
0
0
0
25
0
0
0
25
9
0
0
0
0
25
0
% R
% Ser:
9
9
9
25
9
9
34
42
25
9
34
17
0
0
34
% S
% Thr:
42
9
0
9
0
0
0
0
0
34
0
9
25
0
9
% T
% Val:
0
34
9
0
0
0
0
0
34
17
17
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _