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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSNARE1 All Species: 9.09
Human Site: S375 Identified Species: 18.18
UniProt: Q96NA8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96NA8 NP_659440.2 513 55949 S375 L P M A Q R G S K Q S P Q A P
Chimpanzee Pan troglodytes XP_519987 827 88732 S375 L P M A Q R G S K Q S P Q A P
Rhesus Macaque Macaca mulatta XP_001089591 511 55788 S375 L P M A Q R G S K Q S P Q A P
Dog Lupus familis XP_539185 510 54763 G371 L P T A Q R G G K Q Q S P R G
Cat Felis silvestris
Mouse Mus musculus Q9ER00 274 31177 D145 G S R L S A E D R Q R E E Q L
Rat Rattus norvegicus O70257 261 29832 G131 A S S R V S G G F P E D S S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518833 249 28356 E120 G S R L S V E E R H R E E Q L
Chicken Gallus gallus
Frog Xenopus laevis NP_001079671 259 29246 F130 G S R V S G G F P D D N Q K E
Zebra Danio Brachydanio rerio XP_697581 267 30970 Q138 A R A G S R F Q V D E L N Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623620 281 32229 M152 Q K S I V E K M K R H I L L T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39233 279 31043 A150 E I P T S Y N A P E L D T E S
Baker's Yeast Sacchar. cerevisiae P32854 288 32988 A158 S E M A N D A A L L D E E Q R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.4 95.7 79.9 N.A. 22.8 20 N.A. 21.8 N.A. 23 22 N.A. N.A. 20.6 N.A. N.A.
Protein Similarity: 100 61.4 96.4 86.1 N.A. 37.8 33.5 N.A. 34.1 N.A. 33.7 35.4 N.A. N.A. 36 N.A. N.A.
P-Site Identity: 100 100 100 53.3 N.A. 6.6 6.6 N.A. 0 N.A. 13.3 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 53.3 N.A. 20 13.3 N.A. 13.3 N.A. 13.3 6.6 N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 35.6 35.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 9 42 0 9 9 17 0 0 0 0 0 25 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 9 0 17 17 17 0 0 9 % D
% Glu: 9 9 0 0 0 9 17 9 0 9 17 25 25 9 9 % E
% Phe: 0 0 0 0 0 0 9 9 9 0 0 0 0 0 0 % F
% Gly: 25 0 0 9 0 9 50 17 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % H
% Ile: 0 9 0 9 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 9 0 0 0 0 9 0 42 0 0 0 0 9 9 % K
% Leu: 34 0 0 17 0 0 0 0 9 9 9 9 9 9 17 % L
% Met: 0 0 34 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 9 0 0 0 0 9 9 0 0 % N
% Pro: 0 34 9 0 0 0 0 0 17 9 0 25 9 0 25 % P
% Gln: 9 0 0 0 34 0 0 9 0 42 9 0 34 34 0 % Q
% Arg: 0 9 25 9 0 42 0 0 17 9 17 0 0 9 9 % R
% Ser: 9 34 17 0 42 9 0 25 0 0 25 9 9 9 9 % S
% Thr: 0 0 9 9 0 0 0 0 0 0 0 0 9 0 9 % T
% Val: 0 0 0 9 17 9 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _