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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC25 All Species: 13.94
Human Site: Y323 Identified Species: 38.33
UniProt: Q96NG3 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96NG3 NP_113609.1 672 76655 Y323 D E L V G N L Y S C I G N A Q
Chimpanzee Pan troglodytes XP_001167294 672 76635 Y323 D E L V G N L Y S C I G N A Q
Rhesus Macaque Macaca mulatta XP_001108266 671 76498 Y323 D E L V G N L Y S C I G N A Q
Dog Lupus familis XP_548096 689 78844 Y323 D E L V G N L Y S C I G N A Q
Cat Felis silvestris
Mouse Mus musculus Q9D4B2 624 71511 N306 L K K V L E W N Q E E V P N K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521199 616 68061 S298 L A R Y I L K S L E D I D M L
Chicken Gallus gallus
Frog Xenopus laevis Q32NU8 531 60936 G214 R D E A L V K G N T R G G V K
Zebra Danio Brachydanio rerio Q7ZU45 486 55562 K169 S N K K E S K K H S K K T D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786290 649 73811 H326 Q D F I A N L H S C L G N A Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 93.1 79.3 N.A. 75.8 N.A. N.A. 56.2 N.A. 49.7 41.5 N.A. N.A. N.A. N.A. 43.6
Protein Similarity: 100 98 94.6 86.3 N.A. 82.5 N.A. N.A. 69.3 N.A. 63.9 56.2 N.A. N.A. N.A. N.A. 64.4
P-Site Identity: 100 100 100 100 N.A. 6.6 N.A. N.A. 0 N.A. 6.6 0 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 20 N.A. N.A. 6.6 N.A. 26.6 13.3 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 12 12 0 0 0 0 0 0 0 0 56 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 56 0 0 0 0 0 % C
% Asp: 45 23 0 0 0 0 0 0 0 0 12 0 12 12 0 % D
% Glu: 0 45 12 0 12 12 0 0 0 23 12 0 0 0 0 % E
% Phe: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 45 0 0 12 0 0 0 67 12 0 0 % G
% His: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 12 0 0 0 0 0 45 12 0 0 0 % I
% Lys: 0 12 23 12 0 0 34 12 0 0 12 12 0 0 34 % K
% Leu: 23 0 45 0 23 12 56 0 12 0 12 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 12 0 0 0 56 0 12 12 0 0 0 56 12 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % P
% Gln: 12 0 0 0 0 0 0 0 12 0 0 0 0 0 45 % Q
% Arg: 12 0 12 0 0 0 0 0 0 0 12 0 0 0 0 % R
% Ser: 12 0 0 0 0 12 0 12 56 12 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 12 0 0 12 0 0 % T
% Val: 0 0 0 56 0 12 0 0 0 0 0 12 0 12 0 % V
% Trp: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 45 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _