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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC25
All Species:
12.12
Human Site:
Y499
Identified Species:
33.33
UniProt:
Q96NG3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NG3
NP_113609.1
672
76655
Y499
R
E
L
R
K
T
N
Y
V
E
N
L
K
E
K
Chimpanzee
Pan troglodytes
XP_001167294
672
76635
Y499
G
E
L
R
K
T
N
Y
M
E
N
L
K
E
K
Rhesus Macaque
Macaca mulatta
XP_001108266
671
76498
Y499
G
E
L
R
K
T
N
Y
M
E
N
L
K
E
K
Dog
Lupus familis
XP_548096
689
78844
Y499
E
E
L
K
K
T
D
Y
R
E
M
L
R
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4B2
624
71511
F458
F
E
S
A
V
N
N
F
E
K
A
L
E
R
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521199
616
68061
E450
R
S
L
Q
A
A
E
E
E
G
D
V
E
W
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q32NU8
531
60936
I366
K
S
R
A
L
D
N
I
G
R
V
Y
A
R
I
Zebra Danio
Brachydanio rerio
Q7ZU45
486
55562
G321
G
N
L
H
S
Y
I
G
N
A
L
M
D
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786290
649
73811
I482
D
E
P
A
Q
K
A
I
A
S
A
L
E
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
93.1
79.3
N.A.
75.8
N.A.
N.A.
56.2
N.A.
49.7
41.5
N.A.
N.A.
N.A.
N.A.
43.6
Protein Similarity:
100
98
94.6
86.3
N.A.
82.5
N.A.
N.A.
69.3
N.A.
63.9
56.2
N.A.
N.A.
N.A.
N.A.
64.4
P-Site Identity:
100
86.6
86.6
53.3
N.A.
20
N.A.
N.A.
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
80
N.A.
40
N.A.
N.A.
46.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
12
12
12
0
12
12
23
0
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
12
12
0
0
0
12
0
12
12
0
% D
% Glu:
12
67
0
0
0
0
12
12
23
45
0
0
34
45
0
% E
% Phe:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
34
0
0
0
0
0
0
12
12
12
0
0
0
0
12
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
23
0
0
0
0
0
0
12
% I
% Lys:
12
0
0
12
45
12
0
0
0
12
0
0
34
0
34
% K
% Leu:
0
0
67
0
12
0
0
0
0
0
12
67
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
23
0
12
12
0
0
0
% M
% Asn:
0
12
0
0
0
12
56
0
12
0
34
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
23
0
12
34
0
0
0
0
12
12
0
0
12
23
12
% R
% Ser:
0
23
12
0
12
0
0
0
0
12
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
45
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
12
0
12
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
12
0
45
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _