KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM74
All Species:
10.91
Human Site:
S267
Identified Species:
40
UniProt:
Q96NL1
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NL1
NP_694560.1
305
33338
S267
Y
R
R
N
R
F
A
S
S
K
E
S
A
K
L
Chimpanzee
Pan troglodytes
XP_001167747
422
45110
P378
Y
R
R
R
T
F
V
P
G
K
G
S
R
K
T
Rhesus Macaque
Macaca mulatta
XP_001091064
305
33386
S267
Y
R
R
N
R
F
A
S
S
K
E
S
A
K
L
Dog
Lupus familis
XP_851952
293
31793
T256
P
G
R
G
S
G
K
T
Y
G
S
I
N
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQU7
305
33398
S267
Y
R
R
N
R
F
A
S
S
K
E
S
A
K
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418386
280
30483
D243
A
R
I
G
A
H
L
D
R
C
V
I
A
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921454
280
30650
S243
R
R
K
A
F
A
Y
S
K
H
S
A
K
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.8
97.3
32.7
N.A.
77.3
N.A.
N.A.
N.A.
50.4
N.A.
45.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
42.8
98.6
49.1
N.A.
86.5
N.A.
N.A.
N.A.
60.9
N.A.
59
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
100
6.6
N.A.
100
N.A.
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
13.3
N.A.
100
N.A.
N.A.
N.A.
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
15
15
15
43
0
0
0
0
15
58
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% E
% Phe:
0
0
0
0
15
58
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
0
29
0
15
0
0
15
15
15
0
0
15
0
% G
% His:
0
0
0
0
0
15
0
0
0
15
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
0
0
0
0
29
0
0
0
% I
% Lys:
0
0
15
0
0
0
15
0
15
58
0
0
15
58
0
% K
% Leu:
0
0
0
0
0
0
15
0
0
0
0
0
0
29
58
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
43
0
0
0
0
0
0
0
0
15
0
0
% N
% Pro:
15
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
86
72
15
43
0
0
0
15
0
0
0
15
0
15
% R
% Ser:
0
0
0
0
15
0
0
58
43
0
29
58
0
0
0
% S
% Thr:
0
0
0
0
15
0
0
15
0
0
0
0
0
0
15
% T
% Val:
0
0
0
0
0
0
15
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
58
0
0
0
0
0
15
0
15
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _