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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AIFM3 All Species: 26.67
Human Site: S414 Identified Species: 58.67
UniProt: Q96NN9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96NN9 NP_001018070.1 605 66791 S414 L K E V V L K S S K V V R A D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001085679 1362 152397 S414 L K E V V L K S S K V V R A D
Dog Lupus familis XP_543566 807 86690 S640 L K E V V L K S S K V V R A D
Cat Felis silvestris
Mouse Mus musculus Q3TY86 605 66774 S414 L Q E V V L K S S K V L R A D
Rat Rattus norvegicus NP_001013999 604 66626 S413 L Q E V V L K S S K V L R A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415290 591 65258 R428 M K M F E S H R V K F Y M Q T
Frog Xenopus laevis NP_001081029 605 66987 S414 L K E V V L K S G K V L R A D
Zebra Danio Brachydanio rerio NP_001121885 599 65822 S414 L K E V V L K S G K V L R A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569976 593 64987 D401 V S E V V L V D D T R L P C D
Honey Bee Apis mellifera XP_625035 578 64311 D381 V G T V V L N D D Q I L P A D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92947 493 53283 G337 I G G I Q V D G L F R T S T P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 43.8 69 N.A. 96 95.8 N.A. N.A. 72.2 77.6 65.9 N.A. 35.7 34.3 N.A. N.A.
Protein Similarity: 100 N.A. 44.2 69.6 N.A. 98 97.8 N.A. N.A. 81.8 89.9 81.4 N.A. 55.5 56 N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 86.6 86.6 N.A. N.A. 13.3 86.6 86.6 N.A. 33.3 33.3 N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 20 93.3 93.3 N.A. 46.6 60 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 73 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 10 19 19 0 0 0 0 0 82 % D
% Glu: 0 0 73 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 10 10 0 0 0 0 % F
% Gly: 0 19 10 0 0 0 0 10 19 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 55 0 0 0 0 64 0 0 73 0 0 0 0 0 % K
% Leu: 64 0 0 0 0 82 0 0 10 0 0 55 0 0 0 % L
% Met: 10 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 10 % P
% Gln: 0 19 0 0 10 0 0 0 0 10 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 19 0 64 0 0 % R
% Ser: 0 10 0 0 0 10 0 64 46 0 0 0 10 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 10 0 10 0 10 10 % T
% Val: 19 0 0 82 82 10 10 0 10 0 64 28 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _