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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIFM3
All Species:
24.55
Human Site:
T395
Identified Species:
54
UniProt:
Q96NN9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NN9
NP_001018070.1
605
66791
T395
R
V
K
F
Y
M
Q
T
E
V
S
E
L
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085679
1362
152397
T395
R
V
K
F
Y
M
Q
T
E
V
S
E
L
R
G
Dog
Lupus familis
XP_543566
807
86690
T621
R
V
K
F
Y
M
Q
T
E
V
S
E
L
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TY86
605
66774
T395
R
V
K
F
Y
M
Q
T
E
V
S
E
L
R
A
Rat
Rattus norvegicus
NP_001013999
604
66626
T394
R
V
K
F
Y
M
Q
T
E
V
S
E
L
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415290
591
65258
K410
L
E
E
V
P
F
K
K
F
F
G
E
R
V
G
Frog
Xenopus laevis
NP_001081029
605
66987
T395
R
V
K
F
Y
M
Q
T
E
V
S
E
L
R
E
Zebra Danio
Brachydanio rerio
NP_001121885
599
65822
N395
R
V
K
F
Y
M
L
N
E
V
W
E
M
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569976
593
64987
S381
K
V
V
M
R
M
E
S
G
I
A
E
I
V
G
Honey Bee
Apis mellifera
XP_625035
578
64311
H359
G
I
K
F
I
F
E
H
D
I
T
Q
F
V
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92947
493
53283
G319
I
G
A
K
P
A
I
G
P
F
E
T
L
A
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
43.8
69
N.A.
96
95.8
N.A.
N.A.
72.2
77.6
65.9
N.A.
35.7
34.3
N.A.
N.A.
Protein Similarity:
100
N.A.
44.2
69.6
N.A.
98
97.8
N.A.
N.A.
81.8
89.9
81.4
N.A.
55.5
56
N.A.
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
93.3
73.3
N.A.
26.6
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
26.6
93.3
80
N.A.
66.6
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
0
0
10
0
0
10
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
10
0
0
0
19
0
64
0
10
82
0
0
10
% E
% Phe:
0
0
0
73
0
19
0
0
10
19
0
0
10
0
0
% F
% Gly:
10
10
0
0
0
0
0
10
10
0
10
0
0
0
46
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
10
0
10
0
0
19
0
0
10
0
0
% I
% Lys:
10
0
73
10
0
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
10
0
0
0
0
0
64
0
0
% L
% Met:
0
0
0
10
0
73
0
0
0
0
0
0
10
0
10
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
19
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
55
0
0
0
0
10
0
0
0
% Q
% Arg:
64
0
0
0
10
0
0
0
0
0
0
0
10
64
0
% R
% Ser:
0
0
0
0
0
0
0
10
0
0
55
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
55
0
0
10
10
0
0
0
% T
% Val:
0
73
10
10
0
0
0
0
0
64
0
0
0
28
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _