KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTCHD1
All Species:
14.55
Human Site:
Y591
Identified Species:
40
UniProt:
Q96NR3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NR3
NP_775766.2
888
101341
Y591
R
I
S
W
F
E
S
Y
L
N
Y
L
R
K
L
Chimpanzee
Pan troglodytes
XP_520973
774
88355
G489
R
K
L
N
V
S
T
G
L
P
K
K
N
F
T
Rhesus Macaque
Macaca mulatta
XP_001088008
888
101335
Y591
R
I
S
W
F
E
S
Y
L
N
Y
L
R
K
L
Dog
Lupus familis
XP_849603
888
101349
Y591
R
I
S
W
F
E
S
Y
L
N
Y
L
R
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q14B62
888
101517
Y591
R
I
S
W
F
E
S
Y
L
N
Y
L
R
K
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515853
517
58837
P234
L
N
V
S
T
G
L
P
K
K
N
F
T
D
T
Chicken
Gallus gallus
XP_425565
782
89369
P499
L
N
I
S
T
G
L
P
K
K
N
F
T
D
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RIV7
897
102365
D593
F
N
K
I
S
W
I
D
N
Y
F
H
F
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03602
844
95994
Y561
R
D
L
G
G
S
E
Y
S
S
P
S
E
F
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.1
99.7
99.2
N.A.
97.9
N.A.
N.A.
49.6
82.5
N.A.
49.2
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
100
87.1
99.8
99.8
N.A.
98.9
N.A.
N.A.
53.9
86.1
N.A.
71.3
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
N.A.
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
N.A.
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
12
0
0
0
0
0
23
0
% D
% Glu:
0
0
0
0
0
45
12
0
0
0
0
0
12
0
0
% E
% Phe:
12
0
0
0
45
0
0
0
0
0
12
23
12
23
0
% F
% Gly:
0
0
0
12
12
23
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
45
12
12
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
12
0
0
0
0
0
23
23
12
12
0
45
0
% K
% Leu:
23
0
23
0
0
0
23
0
56
0
0
45
0
12
45
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
34
0
12
0
0
0
0
12
45
23
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
23
0
12
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
67
0
0
0
0
0
0
0
0
0
0
0
45
0
12
% R
% Ser:
0
0
45
23
12
23
45
0
12
12
0
12
0
0
0
% S
% Thr:
0
0
0
0
23
0
12
0
0
0
0
0
23
0
23
% T
% Val:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
45
0
12
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
0
0
0
0
0
0
56
0
12
45
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _