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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RDH12 All Species: 7.88
Human Site: S190 Identified Species: 14.44
UniProt: Q96NR8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96NR8 NP_689656.2 316 35094 S190 I P F H D L Q S E K R Y S R G
Chimpanzee Pan troglodytes XP_510021 635 69387 T444 R L L G T A G T E E K K K L I
Rhesus Macaque Macaca mulatta XP_001108235 316 35158 S190 I R F H D L Q S E K R Y S R G
Dog Lupus familis XP_547866 303 33635 G177 I H F H D L Q G E K R Y S R G
Cat Felis silvestris
Mouse Mus musculus Q8BYK4 316 35274 G190 I R F H D L Q G Q K R Y C S A
Rat Rattus norvegicus Q6AYS8 298 32919 A174 V V T V A S A A G H T V V P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521365 217 24366 K93 F H D L Q G E K Y Y Y S N M A
Chicken Gallus gallus Q5F389 414 46711 K284 F S L L S P S K K E Y W A M L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q803A8 412 46303 Q281 L D L L S P P Q K N Y W S L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLU5 409 46492 P279 V H H L S P P P E K Y W S M M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798545 322 35072 S178 N S D Q R Y N S A E A Y A N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42536 405 43844 K281 F V G A K A Y K D S K V C N M
Baker's Yeast Sacchar. cerevisiae Q08651 330 37466 S205 T W F R Y A M S K T A L I Q C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 98.4 88.6 N.A. 86.3 24.6 N.A. 55.3 34.2 N.A. 33.2 N.A. 29.8 N.A. N.A. 46.5
Protein Similarity: 100 40.3 99 92 N.A. 90.1 38.9 N.A. 60.4 47.5 N.A. 47.5 N.A. 44.9 N.A. N.A. 67
P-Site Identity: 100 6.6 93.3 86.6 N.A. 60 0 N.A. 0 0 N.A. 6.6 N.A. 20 N.A. N.A. 13.3
P-Site Similarity: 100 26.6 93.3 86.6 N.A. 66.6 13.3 N.A. 13.3 26.6 N.A. 26.6 N.A. 33.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 29.3 25.7 N.A.
Protein Similarity: N.A. N.A. N.A. 45.6 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 24 8 8 8 0 16 0 16 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 8 % C
% Asp: 0 8 16 0 31 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 39 24 0 0 0 0 0 % E
% Phe: 24 0 39 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 8 8 0 8 8 16 8 0 0 0 0 0 24 % G
% His: 0 24 8 31 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 31 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % I
% Lys: 0 0 0 0 8 0 0 24 24 39 16 8 8 0 0 % K
% Leu: 8 8 24 31 0 31 0 0 0 0 0 8 0 16 16 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 24 16 % M
% Asn: 8 0 0 0 0 0 8 0 0 8 0 0 8 16 0 % N
% Pro: 0 8 0 0 0 24 16 8 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 8 8 0 31 8 8 0 0 0 0 8 0 % Q
% Arg: 8 16 0 8 8 0 0 0 0 0 31 0 0 24 0 % R
% Ser: 0 16 0 0 24 8 8 31 0 8 0 8 39 8 8 % S
% Thr: 8 0 8 0 8 0 0 8 0 8 8 0 0 0 0 % T
% Val: 16 16 0 8 0 0 0 0 0 0 0 16 8 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 24 0 0 0 % W
% Tyr: 0 0 0 0 8 8 8 0 8 8 31 39 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _