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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RDH12 All Species: 26.67
Human Site: S265 Identified Species: 48.89
UniProt: Q96NR8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96NR8 NP_689656.2 316 35094 S265 A R E G A Q T S L H C A L A E
Chimpanzee Pan troglodytes XP_510021 635 69387 G519 G R G D M K Y G I Y A V E N E
Rhesus Macaque Macaca mulatta XP_001108235 316 35158 S265 A R E G A Q T S L H C A L A E
Dog Lupus familis XP_547866 303 33635 S252 A R E G A Q T S L H C A L A E
Cat Felis silvestris
Mouse Mus musculus Q8BYK4 316 35274 S265 T S Q G A Q T S L H C A L A E
Rat Rattus norvegicus Q6AYS8 298 32919 G249 V V E H L M H G I L T N Q K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521365 217 24366 H168 E G A Q T S L H C A V A E N L
Chicken Gallus gallus Q5F389 414 46711 T359 M Q Q G A A T T V Y C A T A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q803A8 412 46303 T356 M Q Q G A A T T V Y C A V A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLU5 409 46492 S354 L Q Q A A A T S I Y C A T A N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798545 322 35072 S253 P Q Q G A Q T S V Y C A V D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42536 405 43844 V356 G K R L A Q V V A D P S L T K
Baker's Yeast Sacchar. cerevisiae Q08651 330 37466 D280 A S L K C A L D P N L S V E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 98.4 88.6 N.A. 86.3 24.6 N.A. 55.3 34.2 N.A. 33.2 N.A. 29.8 N.A. N.A. 46.5
Protein Similarity: 100 40.3 99 92 N.A. 90.1 38.9 N.A. 60.4 47.5 N.A. 47.5 N.A. 44.9 N.A. N.A. 67
P-Site Identity: 100 13.3 100 100 N.A. 80 6.6 N.A. 6.6 40 N.A. 40 N.A. 40 N.A. N.A. 46.6
P-Site Similarity: 100 33.3 100 100 N.A. 86.6 13.3 N.A. 6.6 73.3 N.A. 80 N.A. 66.6 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 29.3 25.7 N.A.
Protein Similarity: N.A. N.A. N.A. 45.6 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 0 8 8 70 31 0 0 8 8 8 70 0 54 8 % A
% Cys: 0 0 0 0 8 0 0 0 8 0 62 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 8 0 8 0 0 0 8 0 % D
% Glu: 8 0 31 0 0 0 0 0 0 0 0 0 16 8 39 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 8 8 54 0 0 0 16 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 8 8 0 31 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 24 0 0 0 0 0 0 % I
% Lys: 0 8 0 8 0 8 0 0 0 0 0 0 0 8 16 % K
% Leu: 8 0 8 8 8 0 16 0 31 8 8 0 39 0 8 % L
% Met: 16 0 0 0 8 8 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 8 0 16 8 % N
% Pro: 8 0 0 0 0 0 0 0 8 0 8 0 0 0 16 % P
% Gln: 0 31 39 8 0 47 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 31 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 16 0 0 0 8 0 47 0 0 0 16 0 0 0 % S
% Thr: 8 0 0 0 8 0 62 16 0 0 8 0 16 8 0 % T
% Val: 8 8 0 0 0 0 8 8 24 0 8 8 24 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 39 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _