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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DACH2
All Species:
11.21
Human Site:
S176
Identified Species:
41.11
UniProt:
Q96NX9
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NX9
NP_001132986.1
599
65323
S176
T
R
K
Q
A
V
N
S
S
R
P
G
R
P
P
Chimpanzee
Pan troglodytes
XP_522679
709
73348
T178
P
G
K
P
V
Y
S
T
P
S
P
V
E
N
T
Rhesus Macaque
Macaca mulatta
XP_001082626
706
72982
G255
V
R
I
L
R
G
L
G
A
I
Q
P
G
V
N
Dog
Lupus familis
XP_851040
606
65866
S183
T
R
K
Q
A
V
N
S
S
R
P
G
R
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q925Q8
634
68570
S183
T
R
K
Q
A
V
N
S
S
R
P
G
R
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512764
643
69802
K154
A
A
M
A
E
A
M
K
L
Q
K
M
K
L
M
Chicken
Gallus gallus
NP_990126
607
65060
S164
N
D
C
T
N
A
S
S
R
P
G
R
P
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
38.2
90.2
N.A.
88.1
N.A.
N.A.
55.8
75.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50.9
51.4
92.4
N.A.
90.8
N.A.
N.A.
65.3
83.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
100
N.A.
100
N.A.
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
13.3
100
N.A.
100
N.A.
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
0
15
43
29
0
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
15
0
0
0
0
0
0
0
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
0
0
0
15
0
15
0
0
15
43
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
0
0
15
0
0
0
0
0
% I
% Lys:
0
0
58
0
0
0
0
15
0
0
15
0
15
0
15
% K
% Leu:
0
0
0
15
0
0
15
0
15
0
0
0
0
15
0
% L
% Met:
0
0
15
0
0
0
15
0
0
0
0
15
0
0
15
% M
% Asn:
15
0
0
0
15
0
43
0
0
0
0
0
0
15
15
% N
% Pro:
15
0
0
15
0
0
0
0
15
15
58
15
15
58
43
% P
% Gln:
0
0
0
43
0
0
0
0
0
15
15
0
0
0
0
% Q
% Arg:
0
58
0
0
15
0
0
0
15
43
0
15
43
0
0
% R
% Ser:
0
0
0
0
0
0
29
58
43
15
0
0
0
0
0
% S
% Thr:
43
0
0
15
0
0
0
15
0
0
0
0
0
0
15
% T
% Val:
15
0
0
0
15
43
0
0
0
0
0
15
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _