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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLIC6
All Species:
20
Human Site:
Y618
Identified Species:
48.89
UniProt:
Q96NY7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NY7
NP_444507.1
704
73012
Y618
L
P
D
E
I
D
A
Y
S
T
E
D
V
T
V
Chimpanzee
Pan troglodytes
XP_001168030
674
69927
Y588
L
P
D
E
I
D
A
Y
S
T
E
D
V
T
V
Rhesus Macaque
Macaca mulatta
XP_001087698
686
71158
Y600
L
P
D
E
I
D
A
Y
S
T
E
D
A
T
V
Dog
Lupus familis
XP_544870
251
28413
T171
A
Y
S
T
E
D
I
T
V
S
G
R
K
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHB9
596
62867
D510
L
P
D
E
I
D
A
D
S
S
E
D
V
T
V
Rat
Rattus norvegicus
Q811Q2
612
64668
Y526
L
P
D
E
I
D
A
Y
S
T
E
D
V
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511421
321
36053
S241
R
G
D
E
E
K
V
S
R
R
K
F
L
D
G
Chicken
Gallus gallus
XP_425551
670
70209
Y584
L
P
D
E
I
D
A
Y
S
T
E
E
I
T
V
Frog
Xenopus laevis
NP_001080333
250
28265
V170
N
S
R
E
E
E
R
V
S
K
R
M
F
L
D
Zebra Danio
Brachydanio rerio
NP_998062
408
45237
A328
D
S
M
E
E
E
K
A
S
N
R
R
F
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
88.4
34.7
N.A.
53.5
54.5
N.A.
33
45
27.8
37.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.3
90.4
35.5
N.A.
62.5
62.5
N.A.
38.6
55.8
31.6
47.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
86.6
100
N.A.
13.3
86.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
93.3
100
N.A.
26.6
100
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
60
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
70
0
0
70
0
10
0
0
0
50
0
10
20
% D
% Glu:
0
0
0
90
40
20
0
0
0
0
60
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
20
10
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
60
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
10
10
0
0
10
10
0
10
0
0
% K
% Leu:
60
0
0
0
0
0
0
0
0
0
0
0
10
20
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
10
0
10
10
20
20
0
0
0
% R
% Ser:
0
20
10
0
0
0
0
10
80
20
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
10
0
50
0
0
0
60
0
% T
% Val:
0
0
0
0
0
0
10
10
10
0
0
0
40
0
60
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _