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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUS81
All Species:
13.03
Human Site:
S101
Identified Species:
26.06
UniProt:
Q96NY9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NY9
NP_079404.3
551
61173
S101
D
S
P
S
G
E
N
S
P
A
P
Q
G
R
L
Chimpanzee
Pan troglodytes
XP_522066
556
61559
S101
D
S
L
S
G
E
N
S
P
A
P
Q
G
R
P
Rhesus Macaque
Macaca mulatta
XP_001112794
551
60990
S101
G
S
P
S
G
E
N
S
P
A
P
Q
G
R
P
Dog
Lupus familis
XP_533230
552
61084
S101
S
S
P
S
G
E
K
S
S
T
P
E
G
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZJ0
551
61513
G101
S
S
P
S
G
K
K
G
A
S
K
G
P
P
E
Rat
Rattus norvegicus
Q4KM32
551
61884
R101
S
S
P
S
G
K
K
R
A
S
K
G
P
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXA9
604
67998
N113
S
Q
K
E
P
S
G
N
F
S
E
H
T
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569873
426
49370
Honey Bee
Apis mellifera
XP_001121737
451
52714
N30
R
K
E
A
A
S
R
N
S
D
L
Q
Y
H
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780532
794
88104
M202
H
Y
T
A
W
S
S
M
S
T
L
V
T
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04149
632
72290
S106
R
T
T
T
A
L
R
S
I
V
N
S
C
E
N
Red Bread Mold
Neurospora crassa
Q7SD49
645
73205
T91
K
H
P
K
R
K
R
T
L
E
L
E
S
A
L
Conservation
Percent
Protein Identity:
100
92.8
97.2
85.3
N.A.
81.8
82
N.A.
N.A.
N.A.
N.A.
50
N.A.
35
30.3
N.A.
33.3
Protein Similarity:
100
93.8
98.3
90
N.A.
88
87.4
N.A.
N.A.
N.A.
N.A.
64.2
N.A.
48.6
47.5
N.A.
45
P-Site Identity:
100
86.6
86.6
53.3
N.A.
26.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
86.6
86.6
60
N.A.
40
40
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
0
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
23.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
41.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
17
0
0
0
17
25
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
9
9
0
34
0
0
0
9
9
17
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% F
% Gly:
9
0
0
0
50
0
9
9
0
0
0
17
34
0
9
% G
% His:
9
9
0
0
0
0
0
0
0
0
0
9
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
9
9
9
9
0
25
25
0
0
0
17
0
0
17
0
% K
% Leu:
0
0
9
0
0
9
0
0
9
0
25
0
0
0
25
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
25
17
0
0
9
0
0
0
9
% N
% Pro:
0
0
50
0
9
0
0
0
25
0
34
0
17
25
25
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
34
0
0
0
% Q
% Arg:
17
0
0
0
9
0
25
9
0
0
0
0
0
25
0
% R
% Ser:
34
50
0
50
0
25
9
42
25
25
0
9
9
0
0
% S
% Thr:
0
9
17
9
0
0
0
9
0
17
0
0
17
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _