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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUS81
All Species:
21.82
Human Site:
S178
Identified Species:
43.64
UniProt:
Q96NY9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NY9
NP_079404.3
551
61173
S178
S
P
R
V
A
P
G
S
A
R
P
W
P
A
L
Chimpanzee
Pan troglodytes
XP_522066
556
61559
S178
S
P
R
V
A
P
G
S
A
R
P
W
P
A
L
Rhesus Macaque
Macaca mulatta
XP_001112794
551
60990
S178
A
P
R
V
A
P
G
S
A
R
P
W
P
A
L
Dog
Lupus familis
XP_533230
552
61084
S178
A
P
R
V
A
L
G
S
T
R
P
W
P
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZJ0
551
61513
S178
T
P
R
V
V
P
G
S
S
K
P
W
P
A
L
Rat
Rattus norvegicus
Q4KM32
551
61884
S178
T
P
R
V
V
P
E
S
S
R
P
W
P
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXA9
604
67998
K190
T
V
P
D
L
G
S
K
Y
T
A
W
S
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569873
426
49370
L82
E
L
R
H
H
R
G
L
Q
L
L
P
Q
E
A
Honey Bee
Apis mellifera
XP_001121737
451
52714
K107
E
Q
N
V
V
K
R
K
C
K
V
Q
T
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780532
794
88104
Y279
S
A
L
E
I
P
N
Y
W
Y
I
D
D
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04149
632
72290
F183
P
N
F
S
T
K
E
F
Y
G
A
W
S
S
I
Red Bread Mold
Neurospora crassa
Q7SD49
645
73205
A168
S
F
T
V
P
T
M
A
N
K
S
Y
T
A
W
Conservation
Percent
Protein Identity:
100
92.8
97.2
85.3
N.A.
81.8
82
N.A.
N.A.
N.A.
N.A.
50
N.A.
35
30.3
N.A.
33.3
Protein Similarity:
100
93.8
98.3
90
N.A.
88
87.4
N.A.
N.A.
N.A.
N.A.
64.2
N.A.
48.6
47.5
N.A.
45
P-Site Identity:
100
100
93.3
80
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
23.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
41.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
34
0
0
9
25
0
17
0
0
59
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
0
% D
% Glu:
17
0
0
9
0
0
17
0
0
0
0
0
0
9
0
% E
% Phe:
0
9
9
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
50
0
0
9
0
0
0
0
9
% G
% His:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
0
0
0
0
17
0
17
0
25
0
0
0
0
0
% K
% Leu:
0
9
9
0
9
9
0
9
0
9
9
0
0
0
50
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
9
0
9
0
0
0
0
0
0
% N
% Pro:
9
50
9
0
9
50
0
0
0
0
50
9
50
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
9
0
0
9
9
0
0
% Q
% Arg:
0
0
59
0
0
9
9
0
0
42
0
0
0
9
0
% R
% Ser:
34
0
0
9
0
0
9
50
17
0
9
0
17
17
0
% S
% Thr:
25
0
9
0
9
9
0
0
9
9
0
0
17
9
9
% T
% Val:
0
9
0
67
25
0
0
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
67
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
9
17
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _