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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUS81
All Species:
31.21
Human Site:
S541
Identified Species:
62.42
UniProt:
Q96NY9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NY9
NP_079404.3
551
61173
S541
P
A
L
S
R
T
L
S
Q
L
Y
C
S
Y
G
Chimpanzee
Pan troglodytes
XP_522066
556
61559
S546
P
A
L
S
R
T
L
S
Q
L
Y
C
S
Y
S
Rhesus Macaque
Macaca mulatta
XP_001112794
551
60990
S541
P
A
L
S
R
T
L
S
Q
L
Y
C
S
Y
S
Dog
Lupus familis
XP_533230
552
61084
S542
P
A
L
S
R
I
F
S
Q
L
Y
C
C
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZJ0
551
61513
Y541
P
A
L
S
R
T
L
Y
Q
L
Y
C
S
H
S
Rat
Rattus norvegicus
Q4KM32
551
61884
Y541
P
A
L
S
R
T
L
Y
Q
L
Y
C
S
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXA9
604
67998
Y594
P
A
L
S
R
T
I
Y
Q
L
Y
C
T
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569873
426
49370
L417
G
D
K
I
S
Q
C
L
H
E
F
Y
S
T
H
Honey Bee
Apis mellifera
XP_001121737
451
52714
Y442
S
V
I
S
K
T
I
Y
Q
L
Y
T
K
K
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780532
794
88104
Y699
P
A
L
S
K
V
V
Y
Q
L
Y
R
S
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04149
632
72290
S622
K
K
I
T
K
S
L
S
E
K
I
Y
D
A
F
Red Bread Mold
Neurospora crassa
Q7SD49
645
73205
L634
R
R
N
V
D
K
G
L
S
E
R
I
A
D
V
Conservation
Percent
Protein Identity:
100
92.8
97.2
85.3
N.A.
81.8
82
N.A.
N.A.
N.A.
N.A.
50
N.A.
35
30.3
N.A.
33.3
Protein Similarity:
100
93.8
98.3
90
N.A.
88
87.4
N.A.
N.A.
N.A.
N.A.
64.2
N.A.
48.6
47.5
N.A.
45
P-Site Identity:
100
93.3
93.3
73.3
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
6.6
33.3
N.A.
53.3
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
13.3
53.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
23.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
41.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
0
0
0
0
0
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
59
9
0
0
% C
% Asp:
0
9
0
0
9
0
0
0
0
0
0
0
9
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
17
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
9
% F
% Gly:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
17
17
% H
% Ile:
0
0
17
9
0
9
17
0
0
0
9
9
0
0
0
% I
% Lys:
9
9
9
0
25
9
0
0
0
9
0
0
9
9
0
% K
% Leu:
0
0
67
0
0
0
50
17
0
75
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
75
0
0
0
0
0
0
% Q
% Arg:
9
9
0
0
59
0
0
0
0
0
9
9
0
9
0
% R
% Ser:
9
0
0
75
9
9
0
42
9
0
0
0
59
9
42
% S
% Thr:
0
0
0
9
0
59
0
0
0
0
0
9
9
9
0
% T
% Val:
0
9
0
9
0
9
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
75
17
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _