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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUS81
All Species:
21.52
Human Site:
T159
Identified Species:
43.03
UniProt:
Q96NY9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NY9
NP_079404.3
551
61173
T159
P
N
G
H
H
F
L
T
K
E
E
L
L
Q
R
Chimpanzee
Pan troglodytes
XP_522066
556
61559
T159
P
N
G
H
H
F
L
T
K
E
E
L
L
Q
R
Rhesus Macaque
Macaca mulatta
XP_001112794
551
60990
T159
P
N
G
Y
Y
F
L
T
K
E
E
L
L
Q
R
Dog
Lupus familis
XP_533230
552
61084
T159
P
S
G
R
S
F
L
T
K
E
E
L
L
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZJ0
551
61513
T159
S
D
G
H
S
F
L
T
K
E
E
L
L
Q
K
Rat
Rattus norvegicus
Q4KM32
551
61884
T159
S
D
G
H
S
F
L
T
K
E
E
L
L
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXA9
604
67998
Q171
F
M
F
R
N
E
L
Q
T
E
A
Q
P
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569873
426
49370
G63
R
D
C
S
I
L
R
G
F
G
G
T
L
C
Q
Honey Bee
Apis mellifera
XP_001121737
451
52714
A88
Q
N
S
D
L
I
N
A
N
D
Y
T
C
E
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780532
794
88104
Q260
D
N
T
I
P
V
A
Q
E
D
Q
R
S
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04149
632
72290
E164
V
S
K
E
Q
I
I
E
V
A
G
K
Y
S
D
Red Bread Mold
Neurospora crassa
Q7SD49
645
73205
T149
K
E
F
M
D
K
T
T
L
I
A
K
A
Q
P
Conservation
Percent
Protein Identity:
100
92.8
97.2
85.3
N.A.
81.8
82
N.A.
N.A.
N.A.
N.A.
50
N.A.
35
30.3
N.A.
33.3
Protein Similarity:
100
93.8
98.3
90
N.A.
88
87.4
N.A.
N.A.
N.A.
N.A.
64.2
N.A.
48.6
47.5
N.A.
45
P-Site Identity:
100
100
86.6
80
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
23.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
41.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
0
9
17
0
9
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
9
9
9
% C
% Asp:
9
25
0
9
9
0
0
0
0
17
0
0
0
0
9
% D
% Glu:
0
9
0
9
0
9
0
9
9
59
50
0
0
17
0
% E
% Phe:
9
0
17
0
0
50
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
50
0
0
0
0
9
0
9
17
0
0
0
0
% G
% His:
0
0
0
34
17
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
17
9
0
0
9
0
0
0
0
0
% I
% Lys:
9
0
9
0
0
9
0
0
50
0
0
17
0
0
17
% K
% Leu:
0
0
0
0
9
9
59
0
9
0
0
50
59
9
0
% L
% Met:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
42
0
0
9
0
9
0
9
0
0
0
0
0
0
% N
% Pro:
34
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% P
% Gln:
9
0
0
0
9
0
0
17
0
0
9
9
0
59
9
% Q
% Arg:
9
0
0
17
0
0
9
0
0
0
0
9
0
0
34
% R
% Ser:
17
17
9
9
25
0
0
0
0
0
0
0
9
9
0
% S
% Thr:
0
0
9
0
0
0
9
59
9
0
0
17
0
0
0
% T
% Val:
9
0
0
0
0
9
0
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
9
0
0
0
0
0
9
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _