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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUS81
All Species:
5.76
Human Site:
T445
Identified Species:
11.52
UniProt:
Q96NY9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NY9
NP_079404.3
551
61173
T445
N
P
E
S
G
A
M
T
S
P
N
P
L
C
S
Chimpanzee
Pan troglodytes
XP_522066
556
61559
T450
N
P
E
S
G
A
M
T
S
P
N
P
L
C
S
Rhesus Macaque
Macaca mulatta
XP_001112794
551
60990
P445
N
P
E
S
G
A
M
P
S
P
N
P
L
C
S
Dog
Lupus familis
XP_533230
552
61084
P446
D
P
E
S
R
P
G
P
S
P
H
P
L
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZJ0
551
61513
P445
A
A
E
S
E
A
K
P
S
T
N
P
L
C
S
Rat
Rattus norvegicus
Q4KM32
551
61884
P445
D
A
E
S
E
A
K
P
S
T
N
P
L
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXA9
604
67998
K497
D
G
E
A
E
S
E
K
M
V
A
N
L
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569873
426
49370
L322
A
I
D
Q
S
T
C
L
L
T
H
S
D
L
G
Honey Bee
Apis mellifera
XP_001121737
451
52714
T347
M
F
Y
L
S
S
L
T
R
I
I
S
N
N
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780532
794
88104
L604
K
L
T
G
S
T
D
L
N
S
P
Q
Q
R
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04149
632
72290
L521
K
D
D
Y
K
K
V
L
L
Q
F
R
R
E
F
Red Bread Mold
Neurospora crassa
Q7SD49
645
73205
V533
A
K
N
Y
L
P
L
V
K
H
L
R
E
K
E
Conservation
Percent
Protein Identity:
100
92.8
97.2
85.3
N.A.
81.8
82
N.A.
N.A.
N.A.
N.A.
50
N.A.
35
30.3
N.A.
33.3
Protein Similarity:
100
93.8
98.3
90
N.A.
88
87.4
N.A.
N.A.
N.A.
N.A.
64.2
N.A.
48.6
47.5
N.A.
45
P-Site Identity:
100
100
93.3
60
N.A.
60
60
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
60
66.6
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
13.3
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
23.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
41.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
17
0
9
0
42
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
50
17
% C
% Asp:
25
9
17
0
0
0
9
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
59
0
25
0
9
0
0
0
0
0
9
9
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
9
% F
% Gly:
0
9
0
9
25
0
9
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
17
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
0
% I
% Lys:
17
9
0
0
9
9
17
9
9
0
0
0
0
9
0
% K
% Leu:
0
9
0
9
9
0
17
25
17
0
9
0
59
9
0
% L
% Met:
9
0
0
0
0
0
25
0
9
0
0
0
0
0
0
% M
% Asn:
25
0
9
0
0
0
0
0
9
0
42
9
9
9
0
% N
% Pro:
0
34
0
0
0
17
0
34
0
34
9
50
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
9
0
9
9
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
9
0
0
17
9
9
0
% R
% Ser:
0
0
0
50
25
17
0
0
50
9
0
17
0
9
50
% S
% Thr:
0
0
9
0
0
17
0
25
0
25
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
9
9
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
17
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _