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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUS81
All Species:
26.97
Human Site:
Y366
Identified Species:
53.94
UniProt:
Q96NY9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NY9
NP_079404.3
551
61173
Y366
C
G
L
E
R
R
V
Y
L
V
E
E
H
G
S
Chimpanzee
Pan troglodytes
XP_522066
556
61559
Y371
C
G
L
E
R
R
V
Y
L
V
E
E
H
G
S
Rhesus Macaque
Macaca mulatta
XP_001112794
551
60990
Y366
C
G
L
E
R
R
V
Y
L
V
E
E
H
G
S
Dog
Lupus familis
XP_533230
552
61084
Y367
C
G
L
G
H
R
V
Y
L
V
E
E
H
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZJ0
551
61513
Y366
C
G
L
G
H
R
V
Y
L
V
E
E
H
G
S
Rat
Rattus norvegicus
Q4KM32
551
61884
Y366
C
G
L
G
H
R
I
Y
L
V
E
E
H
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXA9
604
67998
L418
G
L
R
K
P
I
Y
L
V
E
E
C
G
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569873
426
49370
H243
L
Q
H
C
G
L
Q
H
I
I
Y
L
V
E
D
Honey Bee
Apis mellifera
XP_001121737
451
52714
I268
Y
I
V
E
R
K
R
I
D
D
L
N
A
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780532
794
88104
Y525
C
G
L
G
H
P
V
Y
L
V
E
D
F
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04149
632
72290
Y442
S
G
C
E
H
K
Y
Y
L
I
E
E
T
M
S
Red Bread Mold
Neurospora crassa
Q7SD49
645
73205
I454
G
M
K
N
V
V
Y
I
I
E
N
Y
N
I
D
Conservation
Percent
Protein Identity:
100
92.8
97.2
85.3
N.A.
81.8
82
N.A.
N.A.
N.A.
N.A.
50
N.A.
35
30.3
N.A.
33.3
Protein Similarity:
100
93.8
98.3
90
N.A.
88
87.4
N.A.
N.A.
N.A.
N.A.
64.2
N.A.
48.6
47.5
N.A.
45
P-Site Identity:
100
100
100
86.6
N.A.
86.6
80
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
13.3
N.A.
66.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
20
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
23.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
41.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% A
% Cys:
59
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
9
0
9
0
0
17
% D
% Glu:
0
0
0
42
0
0
0
0
0
17
75
59
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
17
67
0
34
9
0
0
0
0
0
0
0
9
59
0
% G
% His:
0
0
9
0
42
0
0
9
0
0
0
0
50
0
0
% H
% Ile:
0
9
0
0
0
9
9
17
17
17
0
0
0
9
9
% I
% Lys:
0
0
9
9
0
17
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
59
0
0
9
0
9
67
0
9
9
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
9
9
9
0
0
% N
% Pro:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
34
50
9
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
0
0
0
17
67
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
9
0
9
9
50
0
9
59
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
25
67
0
0
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _