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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MUS81 All Species: 30.91
Human Site: Y53 Identified Species: 61.82
UniProt: Q96NY9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96NY9 NP_079404.3 551 61173 Y53 A L R S L R R Y P L P L R S G
Chimpanzee Pan troglodytes XP_522066 556 61559 Y53 A L R S L R R Y P L P L R S G
Rhesus Macaque Macaca mulatta XP_001112794 551 60990 Y53 A L R S L R R Y P L P L R S G
Dog Lupus familis XP_533230 552 61084 Y53 A L R S L R R Y P L P L R S G
Cat Felis silvestris
Mouse Mus musculus Q91ZJ0 551 61513 Y53 A L R S L Q R Y P L P L R S G
Rat Rattus norvegicus Q4KM32 551 61884 Y53 A L R S L Q R Y P L P L R N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SXA9 604 67998 Y54 A I N S L K K Y P L P L K N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569873 426 49370
Honey Bee Apis mellifera XP_001121737 451 52714
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780532 794 88104 Y53 A L V A L K K Y P L P F Q S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04149 632 72290 A43 A K R N L Q N A E G S F Y Y P
Red Bread Mold Neurospora crassa Q7SD49 645 73205 C43 A Y N S L K A C P L T F Q H P
Conservation
Percent
Protein Identity: 100 92.8 97.2 85.3 N.A. 81.8 82 N.A. N.A. N.A. N.A. 50 N.A. 35 30.3 N.A. 33.3
Protein Similarity: 100 93.8 98.3 90 N.A. 88 87.4 N.A. N.A. N.A. N.A. 64.2 N.A. 48.6 47.5 N.A. 45
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. N.A. N.A. N.A. 60 N.A. 0 0 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. N.A. 93.3 N.A. 0 0 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 23.1
Protein Similarity: N.A. N.A. N.A. N.A. 38.9 41.8
P-Site Identity: N.A. N.A. N.A. N.A. 20 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 84 0 0 9 0 0 9 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 67 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 25 17 0 0 0 0 0 9 0 0 % K
% Leu: 0 59 0 0 84 0 0 0 0 75 0 59 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 17 9 0 0 9 0 0 0 0 0 0 17 0 % N
% Pro: 0 0 0 0 0 0 0 0 75 0 67 0 0 0 17 % P
% Gln: 0 0 0 0 0 25 0 0 0 0 0 0 17 0 0 % Q
% Arg: 0 0 59 0 0 34 50 0 0 0 0 0 50 0 0 % R
% Ser: 0 0 0 67 0 0 0 0 0 0 9 0 0 50 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 67 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _