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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSUN5
All Species:
21.21
Human Site:
S116
Identified Species:
31.11
UniProt:
Q96P11
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P11
NP_060514.1
429
46692
S116
L
K
V
H
R
G
V
S
R
N
E
D
L
L
E
Chimpanzee
Pan troglodytes
XP_519138
437
47282
S116
L
K
V
H
R
G
V
S
R
N
E
D
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001110692
429
46730
S116
L
K
V
H
R
G
V
S
R
N
E
D
L
L
E
Dog
Lupus familis
XP_536846
469
51185
S116
L
K
V
Q
R
R
V
S
R
N
E
D
L
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4F6
465
51011
S116
L
K
V
H
R
G
V
S
R
N
E
D
L
L
Q
Rat
Rattus norvegicus
XP_213749
451
49532
G114
A
R
L
K
V
H
R
G
V
S
R
N
E
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514526
433
47383
R97
L
E
P
A
S
G
A
R
P
A
S
K
V
P
R
Chicken
Gallus gallus
XP_415710
465
50976
R116
K
V
R
R
G
V
S
R
N
E
D
L
L
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998450
435
49024
S114
I
K
I
K
R
K
V
S
R
N
Q
D
L
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393743
578
66348
L201
A
A
V
I
T
V
N
L
I
I
A
C
Y
I
Y
Nematode Worm
Caenorhab. elegans
NP_497089
439
49820
G120
E
H
A
M
Q
D
E
G
R
G
I
K
A
M
K
Sea Urchin
Strong. purpuratus
XP_787860
508
56859
G122
Q
K
M
K
E
K
K
G
A
T
S
L
S
D
L
Poplar Tree
Populus trichocarpa
XP_002309481
433
47775
A123
G
D
A
E
K
F
L
A
C
R
K
D
A
M
Q
Maize
Zea mays
NP_001151492
498
55261
M141
G
S
V
E
Q
L
I
M
L
Q
K
D
S
L
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_851079
567
63156
M196
G
D
A
E
K
F
L
M
R
H
K
E
A
L
L
Baker's Yeast
Sacchar. cerevisiae
P53972
490
56159
L137
L
K
L
K
V
R
E
L
S
E
L
V
L
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.4
96.9
81.2
N.A.
81.7
83.8
N.A.
73.4
61
N.A.
57.9
N.A.
N.A.
29.2
35.7
38.9
Protein Similarity:
100
90.6
98.5
85.7
N.A.
86.2
88.6
N.A.
80.1
72.9
N.A.
71
N.A.
N.A.
43.5
55.1
55.3
P-Site Identity:
100
100
100
80
N.A.
93.3
0
N.A.
13.3
6.6
N.A.
60
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
26.6
N.A.
26.6
13.3
N.A.
80
N.A.
N.A.
13.3
26.6
13.3
Percent
Protein Identity:
33.2
30.7
N.A.
28.9
28.5
N.A.
Protein Similarity:
50.3
44.3
N.A.
42.1
48.3
N.A.
P-Site Identity:
6.6
20
N.A.
13.3
26.6
N.A.
P-Site Similarity:
46.6
40
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
7
19
7
0
0
7
7
7
7
7
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% C
% Asp:
0
13
0
0
0
7
0
0
0
0
7
50
0
13
0
% D
% Glu:
7
7
0
19
7
0
13
0
0
13
32
7
7
7
25
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
0
7
32
0
19
0
7
0
0
0
0
0
% G
% His:
0
7
0
25
0
7
0
0
0
7
0
0
0
0
0
% H
% Ile:
7
0
7
7
0
0
7
0
7
7
7
0
0
7
0
% I
% Lys:
7
50
0
25
13
13
7
0
0
0
19
13
0
0
7
% K
% Leu:
44
0
13
0
0
7
13
13
7
0
7
13
50
50
25
% L
% Met:
0
0
7
7
0
0
0
13
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
0
0
0
7
0
7
38
0
7
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
7
0
0
0
0
7
7
% P
% Gln:
7
0
0
7
13
0
0
0
0
7
7
0
0
0
19
% Q
% Arg:
0
7
7
7
38
13
7
13
50
7
7
0
0
0
13
% R
% Ser:
0
7
0
0
7
0
7
38
7
7
13
0
13
7
0
% S
% Thr:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% T
% Val:
0
7
44
0
13
13
38
0
7
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _