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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSUN5
All Species:
18.79
Human Site:
S126
Identified Species:
27.56
UniProt:
Q96P11
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P11
NP_060514.1
429
46692
S126
E
D
L
L
E
V
G
S
R
P
G
P
A
S
Q
Chimpanzee
Pan troglodytes
XP_519138
437
47282
S126
E
D
L
L
E
V
G
S
R
P
G
P
A
S
Q
Rhesus Macaque
Macaca mulatta
XP_001110692
429
46730
S126
E
D
L
L
E
V
G
S
R
P
G
P
V
S
Q
Dog
Lupus familis
XP_536846
469
51185
S126
E
D
L
L
Q
V
G
S
R
P
G
A
A
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4F6
465
51011
S126
E
D
L
L
Q
E
S
S
R
P
G
Q
A
Y
Q
Rat
Rattus norvegicus
XP_213749
451
49532
E124
R
N
E
D
L
L
Q
E
R
P
G
Q
A
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514526
433
47383
R107
S
K
V
P
R
Y
V
R
V
N
T
L
K
T
C
Chicken
Gallus gallus
XP_415710
465
50976
G126
D
L
L
E
L
A
S
G
A
G
P
E
A
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998450
435
49024
I124
Q
D
L
L
P
S
S
I
Q
Q
T
Q
N
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393743
578
66348
L211
A
C
Y
I
Y
Q
A
L
H
E
P
D
N
V
K
Nematode Worm
Caenorhab. elegans
NP_497089
439
49820
D130
I
K
A
M
K
E
A
D
D
G
M
K
K
I
Q
Sea Urchin
Strong. purpuratus
XP_787860
508
56859
S132
S
L
S
D
L
L
P
S
Q
V
K
D
E
V
S
Poplar Tree
Populus trichocarpa
XP_002309481
433
47775
L133
K
D
A
M
Q
S
A
L
A
K
L
V
V
R
K
Maize
Zea mays
NP_001151492
498
55261
L151
K
D
S
L
R
T
T
L
D
K
V
C
A
R
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_851079
567
63156
L206
K
E
A
L
L
S
G
L
A
T
L
L
V
R
K
Baker's Yeast
Sacchar. cerevisiae
P53972
490
56159
S147
L
V
L
S
E
D
I
S
N
D
L
P
P
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.4
96.9
81.2
N.A.
81.7
83.8
N.A.
73.4
61
N.A.
57.9
N.A.
N.A.
29.2
35.7
38.9
Protein Similarity:
100
90.6
98.5
85.7
N.A.
86.2
88.6
N.A.
80.1
72.9
N.A.
71
N.A.
N.A.
43.5
55.1
55.3
P-Site Identity:
100
100
93.3
86.6
N.A.
66.6
33.3
N.A.
0
20
N.A.
20
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
73.3
46.6
N.A.
13.3
26.6
N.A.
33.3
N.A.
N.A.
13.3
20
20
Percent
Protein Identity:
33.2
30.7
N.A.
28.9
28.5
N.A.
Protein Similarity:
50.3
44.3
N.A.
42.1
48.3
N.A.
P-Site Identity:
6.6
20
N.A.
13.3
26.6
N.A.
P-Site Similarity:
33.3
33.3
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
19
0
0
7
19
0
19
0
0
7
44
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
7
% C
% Asp:
7
50
0
13
0
7
0
7
13
7
0
13
0
7
0
% D
% Glu:
32
7
7
7
25
13
0
7
0
7
0
7
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
32
7
0
13
38
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% H
% Ile:
7
0
0
7
0
0
7
7
0
0
0
0
0
7
0
% I
% Lys:
19
13
0
0
7
0
0
0
0
13
7
7
13
0
25
% K
% Leu:
7
13
50
50
25
13
0
25
0
0
19
13
0
0
0
% L
% Met:
0
0
0
13
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
7
7
0
0
13
0
0
% N
% Pro:
0
0
0
7
7
0
7
0
0
38
13
25
7
7
0
% P
% Gln:
7
0
0
0
19
7
7
0
13
7
0
19
0
0
50
% Q
% Arg:
7
0
0
0
13
0
0
7
38
0
0
0
0
19
7
% R
% Ser:
13
0
13
7
0
19
19
44
0
0
0
0
0
25
7
% S
% Thr:
0
0
0
0
0
7
7
0
0
7
13
0
0
7
0
% T
% Val:
0
7
7
0
0
25
7
0
7
7
7
7
19
19
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
7
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _