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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN5 All Species: 16.97
Human Site: S16 Identified Species: 24.89
UniProt: Q96P11 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P11 NP_060514.1 429 46692 S16 G V L A G V E S R Q G S I K G
Chimpanzee Pan troglodytes XP_519138 437 47282 S16 G V L A G V E S R Q G S I K G
Rhesus Macaque Macaca mulatta XP_001110692 429 46730 N16 G V L A G V E N R Q G S I K G
Dog Lupus familis XP_536846 469 51185 S16 S V L A N V E S R R G S I K G
Cat Felis silvestris
Mouse Mus musculus Q8K4F6 465 51011 S16 A V L A G V E S R Q G S L K G
Rat Rattus norvegicus XP_213749 451 49532 S16 A V L A G V E S R Q G S L K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514526 433 47383 D24 A V L D S I I D S A G L L K A
Chicken Gallus gallus XP_415710 465 50976 R16 A V L S G L E R G E G G L K N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998450 435 49024 Q16 E I L E K V E Q K R G A V K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393743 578 66348 E27 K I I Q E V R E K G G S L K S
Nematode Worm Caenorhab. elegans NP_497089 439 49820 A19 E I I R C V L A K E K S V R N
Sea Urchin Strong. purpuratus XP_787860 508 56859 I23 A V I S K A Q I K E K S I K S
Poplar Tree Populus trichocarpa XP_002309481 433 47775 Q43 L Q G D A K R Q A V A S I K S
Maize Zea mays NP_001151492 498 55261 R62 L R G D A T R R A A G S I K S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_851079 567 63156 R117 L R G D A E R R A V A S I K S
Baker's Yeast Sacchar. cerevisiae P53972 490 56159 M27 K E R I S G S M Q T L V L K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.4 96.9 81.2 N.A. 81.7 83.8 N.A. 73.4 61 N.A. 57.9 N.A. N.A. 29.2 35.7 38.9
Protein Similarity: 100 90.6 98.5 85.7 N.A. 86.2 88.6 N.A. 80.1 72.9 N.A. 71 N.A. N.A. 43.5 55.1 55.3
P-Site Identity: 100 100 93.3 80 N.A. 86.6 86.6 N.A. 26.6 40 N.A. 33.3 N.A. N.A. 26.6 13.3 26.6
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 40 66.6 N.A. 66.6 N.A. N.A. 53.3 60 60
Percent
Protein Identity: 33.2 30.7 N.A. 28.9 28.5 N.A.
Protein Similarity: 50.3 44.3 N.A. 42.1 48.3 N.A.
P-Site Identity: 20 26.6 N.A. 20 6.6 N.A.
P-Site Similarity: 20 26.6 N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 32 0 0 38 19 7 0 7 19 13 13 7 0 0 7 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 25 0 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 13 7 0 7 7 7 50 7 0 19 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 19 0 19 0 38 7 0 0 7 7 69 7 0 0 38 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 19 19 7 0 7 7 7 0 0 0 0 50 0 0 % I
% Lys: 13 0 0 0 13 7 0 0 25 0 13 0 0 94 0 % K
% Leu: 19 0 57 0 0 7 7 0 0 0 7 7 38 0 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 13 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 7 0 0 7 13 7 32 0 0 0 0 0 % Q
% Arg: 0 13 7 7 0 0 25 19 38 13 0 0 0 7 0 % R
% Ser: 7 0 0 13 13 0 7 32 7 0 0 75 0 0 38 % S
% Thr: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 7 % T
% Val: 0 57 0 0 0 57 0 0 0 13 0 7 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _