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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN5 All Species: 28.79
Human Site: S27 Identified Species: 42.22
UniProt: Q96P11 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P11 NP_060514.1 429 46692 S27 S I K G L V Y S S N F Q N V K
Chimpanzee Pan troglodytes XP_519138 437 47282 S27 S I K G L V Y S S N F Q N V K
Rhesus Macaque Macaca mulatta XP_001110692 429 46730 S27 S I K G L V Y S S N F Q N V K
Dog Lupus familis XP_536846 469 51185 A27 S I K G L V Y A S S F Q N V K
Cat Felis silvestris
Mouse Mus musculus Q8K4F6 465 51011 S27 S L K G L V Y S S N F Q N L K
Rat Rattus norvegicus XP_213749 451 49532 S27 S L K G L V Y S S N F Q N L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514526 433 47383 L35 L L K A E K K L R P H L A K V
Chicken Gallus gallus XP_415710 465 50976 G27 G L K N L V Y G S D F P H A R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998450 435 49024 D27 A V K T L V Y D S K F P N I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393743 578 66348 N38 S L K S L I Y N Q R H P N K S
Nematode Worm Caenorhab. elegans NP_497089 439 49820 G30 S V R N A V Y G S S Y K N K K
Sea Urchin Strong. purpuratus XP_787860 508 56859 E34 S I K S L V Y E S N S K N I R
Poplar Tree Populus trichocarpa XP_002309481 433 47775 S54 S I K S L V Y S P S I R N K K
Maize Zea mays NP_001151492 498 55261 S73 S I K S L V Y S P T V R N K R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_851079 567 63156 S128 S I K S L V L S P S V R N K R
Baker's Yeast Sacchar. cerevisiae P53972 490 56159 Y38 V L K S C K R Y K L K S N P K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.4 96.9 81.2 N.A. 81.7 83.8 N.A. 73.4 61 N.A. 57.9 N.A. N.A. 29.2 35.7 38.9
Protein Similarity: 100 90.6 98.5 85.7 N.A. 86.2 88.6 N.A. 80.1 72.9 N.A. 71 N.A. N.A. 43.5 55.1 55.3
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 6.6 40 N.A. 53.3 N.A. N.A. 33.3 40 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 66.6 N.A. 73.3 N.A. N.A. 53.3 73.3 80
Percent
Protein Identity: 33.2 30.7 N.A. 28.9 28.5 N.A.
Protein Similarity: 50.3 44.3 N.A. 42.1 48.3 N.A.
P-Site Identity: 60 53.3 N.A. 46.6 20 N.A.
P-Site Similarity: 73.3 66.6 N.A. 66.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 7 0 0 7 0 0 0 0 7 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % F
% Gly: 7 0 0 38 0 0 0 13 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 13 0 7 0 0 % H
% Ile: 0 50 0 0 0 7 0 0 0 0 7 0 0 13 0 % I
% Lys: 0 0 94 0 0 13 7 0 7 7 7 13 0 38 63 % K
% Leu: 7 38 0 0 82 0 7 7 0 7 0 7 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 7 0 38 0 0 88 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 19 7 0 19 0 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 38 0 0 0 % Q
% Arg: 0 0 7 0 0 0 7 0 7 7 0 19 0 0 25 % R
% Ser: 75 0 0 38 0 0 0 50 63 25 7 7 0 0 7 % S
% Thr: 0 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 7 13 0 0 0 82 0 0 0 0 13 0 0 25 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 82 7 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _