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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN5 All Species: 33.94
Human Site: S315 Identified Species: 49.78
UniProt: Q96P11 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P11 NP_060514.1 429 46692 S315 C S G S G M P S R Q L E E P G
Chimpanzee Pan troglodytes XP_519138 437 47282 S315 C S G S G M P S R Q L E E P G
Rhesus Macaque Macaca mulatta XP_001110692 429 46730 S315 C S G S G M P S R Q L E E P G
Dog Lupus familis XP_536846 469 51185 T315 C S G S G M P T R Q L E E P G
Cat Felis silvestris
Mouse Mus musculus Q8K4F6 465 51011 S315 C S G S G M L S R Q L E E H G
Rat Rattus norvegicus XP_213749 451 49532 S313 C S G S G M L S R Q L E E H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514526 433 47383 S283 C S G S G M V S R R L E E P E
Chicken Gallus gallus XP_415710 465 50976 A315 C S G S G M V A R L P L D E A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998450 435 49024 C313 C S G S G M V C L R D E L P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393743 578 66348 D402 C S G S G M L D R Q I V Y G K
Nematode Worm Caenorhab. elegans NP_497089 439 49820 K323 C S G S G I V K R M D E I T G
Sea Urchin Strong. purpuratus XP_787860 508 56859 S338 C S G S G M A S R K D Y L V D
Poplar Tree Populus trichocarpa XP_002309481 433 47775 A320 C S G S G T A A Q R L D H L L
Maize Zea mays NP_001151492 498 55261 T338 C S G S G I S T E R L D Y L L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_851079 567 63156 T393 C S G S G T I T D R L D H L L
Baker's Yeast Sacchar. cerevisiae P53972 490 56159 G337 C S G S G I F G R K F F D S F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.4 96.9 81.2 N.A. 81.7 83.8 N.A. 73.4 61 N.A. 57.9 N.A. N.A. 29.2 35.7 38.9
Protein Similarity: 100 90.6 98.5 85.7 N.A. 86.2 88.6 N.A. 80.1 72.9 N.A. 71 N.A. N.A. 43.5 55.1 55.3
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 80 46.6 N.A. 53.3 N.A. N.A. 53.3 53.3 53.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 86.6 60 N.A. 60 N.A. N.A. 60 60 60
Percent
Protein Identity: 33.2 30.7 N.A. 28.9 28.5 N.A.
Protein Similarity: 50.3 44.3 N.A. 42.1 48.3 N.A.
P-Site Identity: 40 40 N.A. 40 40 N.A.
P-Site Similarity: 66.6 66.6 N.A. 60 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 13 13 0 0 0 0 0 0 7 % A
% Cys: 100 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 7 0 19 19 13 0 7 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 0 57 44 7 13 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 7 7 0 0 7 % F
% Gly: 0 0 100 0 100 0 0 7 0 0 0 0 0 7 44 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 13 13 0 % H
% Ile: 0 0 0 0 0 19 7 0 0 0 7 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 7 0 13 0 0 0 0 7 % K
% Leu: 0 0 0 0 0 0 19 0 7 7 63 7 13 19 19 % L
% Met: 0 0 0 0 0 69 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 25 0 0 0 7 0 0 38 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 44 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 75 32 0 0 0 0 0 % R
% Ser: 0 100 0 100 0 0 7 44 0 0 0 0 0 7 0 % S
% Thr: 0 0 0 0 0 13 0 19 0 0 0 0 0 7 0 % T
% Val: 0 0 0 0 0 0 25 0 0 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _