Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN5 All Species: 17.58
Human Site: S396 Identified Species: 25.78
UniProt: Q96P11 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P11 NP_060514.1 429 46692 S396 A W P H R G L S T F P G A E H
Chimpanzee Pan troglodytes XP_519138 437 47282 F407 S Y P A L G L F L L Q A S S C
Rhesus Macaque Macaca mulatta XP_001110692 429 46730 S396 A W P H R G L S T F P G A K H
Dog Lupus familis XP_536846 469 51185 S396 S W P H R G L S S F P G A E H
Cat Felis silvestris
Mouse Mus musculus Q8K4F6 465 51011 S396 T W P H R G L S T F P G S E H
Rat Rattus norvegicus XP_213749 451 49532 S394 T W P H R G L S T F P G S E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514526 433 47383 D364 A W P H R G L D T F P D A A R
Chicken Gallus gallus XP_415710 465 50976 A394 S W P C R G L A T F P G A E C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998450 435 49024 R388 L L P D W P E R G H E P L T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393743 578 66348 K487 E W L N F S S K K Y K C S D K
Nematode Worm Caenorhab. elegans NP_497089 439 49820 K406 E W T Y R G L K T Y E V G E H
Sea Urchin Strong. purpuratus XP_787860 508 56859 E426 L S T S Q D G E E D H I G E C
Poplar Tree Populus trichocarpa XP_002309481 433 47775 P406 Q W Q R R G L P V F E G S E H
Maize Zea mays NP_001151492 498 55261 P428 Q W H R R G L P V F Q G S E H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_851079 567 63156 P482 Q W Q R R G L P V F A G S E H
Baker's Yeast Sacchar. cerevisiae P53972 490 56159 D461 F R D G V T Y D P Q Q L A E G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.4 96.9 81.2 N.A. 81.7 83.8 N.A. 73.4 61 N.A. 57.9 N.A. N.A. 29.2 35.7 38.9
Protein Similarity: 100 90.6 98.5 85.7 N.A. 86.2 88.6 N.A. 80.1 72.9 N.A. 71 N.A. N.A. 43.5 55.1 55.3
P-Site Identity: 100 20 93.3 86.6 N.A. 86.6 86.6 N.A. 73.3 73.3 N.A. 6.6 N.A. N.A. 6.6 46.6 6.6
P-Site Similarity: 100 40 100 100 N.A. 93.3 93.3 N.A. 73.3 86.6 N.A. 6.6 N.A. N.A. 33.3 60 13.3
Percent
Protein Identity: 33.2 30.7 N.A. 28.9 28.5 N.A.
Protein Similarity: 50.3 44.3 N.A. 42.1 48.3 N.A.
P-Site Identity: 53.3 53.3 N.A. 53.3 13.3 N.A.
P-Site Similarity: 60 60 N.A. 60 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 7 0 0 0 7 0 0 7 7 38 7 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 19 % C
% Asp: 0 0 7 7 0 7 0 13 0 7 0 7 0 7 0 % D
% Glu: 13 0 0 0 0 0 7 7 7 0 19 0 0 69 0 % E
% Phe: 7 0 0 0 7 0 0 7 0 63 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 75 7 0 7 0 0 57 13 0 7 % G
% His: 0 0 7 38 0 0 0 0 0 7 7 0 0 0 57 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 13 7 0 7 0 0 7 7 % K
% Leu: 13 7 7 0 7 0 75 0 7 7 0 7 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 57 0 0 7 0 19 7 0 44 7 0 0 0 % P
% Gln: 19 0 13 0 7 0 0 0 0 7 19 0 0 0 7 % Q
% Arg: 0 7 0 19 69 0 0 7 0 0 0 0 0 0 7 % R
% Ser: 19 7 0 7 0 7 7 32 7 0 0 0 44 7 0 % S
% Thr: 13 0 13 0 0 7 0 0 44 0 0 0 0 7 0 % T
% Val: 0 0 0 0 7 0 0 0 19 0 0 7 0 0 0 % V
% Trp: 0 75 0 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 0 0 7 0 0 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _