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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSUN5
All Species:
19.7
Human Site:
T325
Identified Species:
28.89
UniProt:
Q96P11
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P11
NP_060514.1
429
46692
T325
L
E
E
P
G
A
G
T
P
S
P
V
R
L
H
Chimpanzee
Pan troglodytes
XP_519138
437
47282
T325
L
E
E
P
G
A
G
T
P
S
P
V
R
L
H
Rhesus Macaque
Macaca mulatta
XP_001110692
429
46730
T325
L
E
E
P
G
A
G
T
P
S
P
A
R
L
H
Dog
Lupus familis
XP_536846
469
51185
T325
L
E
E
P
G
T
G
T
P
S
K
A
R
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4F6
465
51011
T325
L
E
E
H
G
E
G
T
P
S
K
E
R
L
Q
Rat
Rattus norvegicus
XP_213749
451
49532
T323
L
E
E
H
G
E
G
T
P
S
K
E
R
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514526
433
47383
G293
L
E
E
P
E
A
D
G
P
S
P
E
R
L
R
Chicken
Gallus gallus
XP_415710
465
50976
S325
P
L
D
E
A
A
P
S
A
E
R
L
Q
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998450
435
49024
E323
D
E
L
P
E
T
Q
E
D
G
R
L
Q
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393743
578
66348
G412
I
V
Y
G
K
E
K
G
D
P
Q
R
L
K
Q
Nematode Worm
Caenorhab. elegans
NP_497089
439
49820
A333
D
E
I
T
G
G
N
A
E
K
E
R
L
E
K
Sea Urchin
Strong. purpuratus
XP_787860
508
56859
M348
D
Y
L
V
D
D
D
M
Q
E
D
R
A
R
L
Poplar Tree
Populus trichocarpa
XP_002309481
433
47775
R330
L
D
H
L
L
P
S
R
T
T
D
V
V
D
T
Maize
Zea mays
NP_001151492
498
55261
H348
L
D
Y
L
L
P
S
H
S
R
D
S
Q
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_851079
567
63156
H403
L
D
H
L
L
P
S
H
S
E
D
N
N
M
N
Baker's Yeast
Sacchar. cerevisiae
P53972
490
56159
R347
F
F
D
S
F
N
R
R
K
I
D
D
K
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.4
96.9
81.2
N.A.
81.7
83.8
N.A.
73.4
61
N.A.
57.9
N.A.
N.A.
29.2
35.7
38.9
Protein Similarity:
100
90.6
98.5
85.7
N.A.
86.2
88.6
N.A.
80.1
72.9
N.A.
71
N.A.
N.A.
43.5
55.1
55.3
P-Site Identity:
100
100
93.3
73.3
N.A.
66.6
66.6
N.A.
66.6
6.6
N.A.
13.3
N.A.
N.A.
0
13.3
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
66.6
66.6
N.A.
66.6
33.3
N.A.
26.6
N.A.
N.A.
6.6
13.3
0
Percent
Protein Identity:
33.2
30.7
N.A.
28.9
28.5
N.A.
Protein Similarity:
50.3
44.3
N.A.
42.1
48.3
N.A.
P-Site Identity:
13.3
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
26.6
20
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
32
0
7
7
0
0
13
7
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
19
13
0
7
7
13
0
13
0
32
7
0
19
13
% D
% Glu:
0
57
44
7
13
19
0
7
7
19
7
19
0
7
0
% E
% Phe:
7
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
44
7
38
13
0
7
0
0
0
0
0
% G
% His:
0
0
13
13
0
0
0
13
0
0
0
0
0
0
19
% H
% Ile:
7
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
7
0
7
0
7
7
19
0
7
7
7
% K
% Leu:
63
7
13
19
19
0
0
0
0
0
0
13
13
44
19
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
7
7
0
0
0
0
7
7
0
7
% N
% Pro:
7
0
0
38
0
19
7
0
44
7
25
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
7
0
7
0
19
0
25
% Q
% Arg:
0
0
0
0
0
0
7
13
0
7
13
19
44
7
7
% R
% Ser:
0
0
0
7
0
0
19
7
13
44
0
7
0
0
0
% S
% Thr:
0
0
0
7
0
13
0
38
7
7
0
0
0
0
7
% T
% Val:
0
7
0
7
0
0
0
0
0
0
0
19
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
13
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _