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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPRD1A
All Species:
21.52
Human Site:
Y140
Identified Species:
36.41
UniProt:
Q96P16
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P16
NP_060640.2
312
35720
Y140
K
K
P
R
K
R
T
Y
E
Q
I
K
V
D
E
Chimpanzee
Pan troglodytes
XP_001136630
316
36166
Y140
K
K
P
R
K
R
T
Y
E
Q
I
K
V
D
E
Rhesus Macaque
Macaca mulatta
XP_001105423
312
35728
Y140
K
K
P
R
K
R
T
Y
E
Q
I
K
V
D
E
Dog
Lupus familis
XP_866582
318
36360
K146
K
R
T
Y
E
Q
I
K
V
D
E
N
E
N
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDS4
312
35682
Y140
K
K
A
R
K
R
T
Y
E
Q
I
K
V
D
E
Rat
Rattus norvegicus
XP_001056597
417
46600
Y245
K
K
T
R
K
R
T
Y
E
Q
I
K
V
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512622
400
45577
Y228
K
K
S
R
K
R
V
Y
E
Q
I
K
V
D
E
Chicken
Gallus gallus
Q5ZM30
268
30818
R106
S
C
K
K
H
P
G
R
V
L
S
I
W
E
E
Frog
Xenopus laevis
NP_001088920
325
36694
I153
L
K
R
T
F
Q
Q
I
Q
E
E
D
D
D
Y
Zebra Danio
Brachydanio rerio
NP_955850
335
38090
E163
Q
K
V
Q
E
E
E
E
E
E
D
D
D
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396379
332
37569
E160
K
K
S
E
T
E
V
E
V
D
G
T
K
E
L
Nematode Worm
Caenorhab. elegans
P34281
315
36355
V145
G
S
F
P
T
P
A
V
A
N
K
E
H
G
K
Sea Urchin
Strong. purpuratus
XP_779930
352
40189
L179
P
A
T
K
K
P
K
L
E
D
L
Q
R
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05543
409
46470
V142
S
S
P
V
E
A
L
V
L
P
Q
K
L
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
99.6
98.1
N.A.
98.7
73.8
N.A.
71.2
78.2
64
60.9
N.A.
N.A.
49
24.1
46
Protein Similarity:
100
98.7
100
98.1
N.A.
99.3
74.3
N.A.
74.7
83.3
80.3
78.2
N.A.
N.A.
66.8
47.2
63.9
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
86.6
6.6
13.3
13.3
N.A.
N.A.
13.3
0
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
93.3
N.A.
86.6
20
33.3
40
N.A.
N.A.
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
22
8
15
15
50
8
% D
% Glu:
0
0
0
8
22
15
8
15
58
15
15
8
8
15
50
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
0
0
43
8
0
8
0
% I
% Lys:
58
65
8
15
50
0
8
8
0
0
8
50
8
8
8
% K
% Leu:
8
0
0
0
0
0
8
8
8
8
8
0
8
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% N
% Pro:
8
0
29
8
0
22
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
0
0
8
0
15
8
0
8
43
8
8
0
0
0
% Q
% Arg:
0
8
8
43
0
43
0
8
0
0
0
0
8
0
8
% R
% Ser:
15
15
15
0
0
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
22
8
15
0
36
0
0
0
0
8
0
0
0
% T
% Val:
0
0
8
8
0
0
15
15
22
0
0
0
43
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
8
0
0
0
43
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _