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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAP3
All Species:
6.97
Human Site:
T549
Identified Species:
13.94
UniProt:
Q96P50
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P50
NP_085152.2
834
92495
T549
H
S
S
P
R
A
P
T
A
R
R
K
V
R
L
Chimpanzee
Pan troglodytes
XP_516962
964
107827
F715
P
P
E
Q
Q
K
K
F
V
S
K
S
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001093292
957
104871
T645
H
S
S
P
R
V
P
T
A
R
R
K
V
R
L
Dog
Lupus familis
XP_546717
548
59577
T342
S
D
V
L
A
F
S
T
G
S
V
V
D
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQK5
770
87192
I529
P
S
E
Q
E
K
R
I
I
S
K
S
C
E
D
Rat
Rattus norvegicus
Q5FVC7
770
87211
L539
K
S
C
E
D
Q
R
L
S
H
T
R
V
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511466
766
86350
S528
S
H
E
E
K
R
H
S
I
S
K
T
I
P
G
Chicken
Gallus gallus
Q5ZK62
781
88436
T529
V
S
P
L
E
S
R
T
K
V
L
P
Q
S
Q
Frog
Xenopus laevis
NP_001083420
519
59265
L313
P
T
V
V
V
E
D
L
R
L
C
T
V
K
Q
Zebra Danio
Brachydanio rerio
NP_001076484
846
94982
K553
N
S
S
I
R
A
P
K
T
R
R
K
Y
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524458
828
93556
R554
W
A
V
K
K
L
R
R
R
Q
K
Q
R
S
I
Honey Bee
Apis mellifera
XP_392754
905
102393
N626
I
D
N
N
M
E
F
N
I
E
N
E
H
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.4
84.1
61
N.A.
58
57.7
N.A.
55.8
58.7
41.2
72.2
N.A.
36.9
38.5
N.A.
N.A.
Protein Similarity:
100
63.9
85
62.5
N.A.
73.1
73
N.A.
71.2
73.5
50.8
82.5
N.A.
55.2
57.4
N.A.
N.A.
P-Site Identity:
100
0
93.3
6.6
N.A.
6.6
13.3
N.A.
0
13.3
6.6
60
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
13.3
N.A.
13.3
33.3
N.A.
26.6
20
20
66.6
N.A.
40
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
17
0
0
17
0
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
9
0
9
0
0
% C
% Asp:
0
17
0
0
9
0
9
0
0
0
0
0
9
0
9
% D
% Glu:
0
0
25
17
17
17
0
0
0
9
0
9
0
17
9
% E
% Phe:
0
0
0
0
0
9
9
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% G
% His:
17
9
0
0
0
0
9
0
0
9
0
0
9
0
9
% H
% Ile:
9
0
0
9
0
0
0
9
25
0
0
0
9
0
9
% I
% Lys:
9
0
0
9
17
17
9
9
9
0
34
25
0
17
0
% K
% Leu:
0
0
0
17
0
9
0
17
0
9
9
0
0
0
25
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
9
0
0
0
9
0
0
9
0
0
0
0
% N
% Pro:
25
9
9
17
0
0
25
0
0
0
0
9
0
9
0
% P
% Gln:
0
0
0
17
9
9
0
0
0
9
0
9
9
0
17
% Q
% Arg:
0
0
0
0
25
9
34
9
17
25
25
9
9
25
0
% R
% Ser:
17
50
25
0
0
9
9
9
9
34
0
17
9
34
0
% S
% Thr:
0
9
0
0
0
0
0
34
9
0
9
17
0
0
0
% T
% Val:
9
0
25
9
9
9
0
0
9
9
9
9
34
0
17
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _