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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB12
All Species:
20.61
Human Site:
S298
Identified Species:
50.37
UniProt:
Q96P63
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P63
NP_536722.1
405
46276
S298
S
E
E
S
V
V
L
S
F
P
R
F
T
L
E
Chimpanzee
Pan troglodytes
XP_001147068
405
46216
S298
S
E
E
S
V
V
L
S
F
P
R
F
T
L
E
Rhesus Macaque
Macaca mulatta
XP_001090435
405
46411
S298
S
E
E
S
V
V
L
S
F
P
R
F
T
L
E
Dog
Lupus familis
XP_533382
823
92665
S716
S
E
E
T
V
E
V
S
F
P
Q
F
T
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7P9
423
47816
S316
S
E
K
P
V
A
I
S
F
P
Q
F
N
L
E
Rat
Rattus norvegicus
Q4G075
379
42708
K277
H
V
K
L
P
R
F
K
I
E
E
S
Y
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509842
419
47710
S312
A
E
A
Q
V
D
V
S
F
P
Q
F
T
L
Q
Chicken
Gallus gallus
O73790
410
47365
H300
T
E
T
L
V
D
L
H
L
P
K
F
S
L
E
Frog
Xenopus laevis
Q52L45
377
42679
F275
V
H
I
H
L
P
K
F
K
L
E
D
S
Y
K
Zebra Danio
Brachydanio rerio
NP_001009892
384
43337
K282
Q
V
S
L
P
K
F
K
T
E
Q
T
Y
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95
40.9
N.A.
70.2
43.2
N.A.
62
41.2
44.2
45.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
96.7
45.3
N.A.
81
62.4
N.A.
77
63.6
63.4
64.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
60
0
N.A.
53.3
46.6
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
13.3
N.A.
80
66.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
20
0
0
0
0
0
10
0
10
0
% D
% Glu:
0
70
40
0
0
10
0
0
0
20
20
0
0
0
60
% E
% Phe:
0
0
0
0
0
0
20
10
60
0
0
70
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
10
0
10
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
10
0
0
0
0
10
0
% I
% Lys:
0
0
20
0
0
10
10
20
10
0
10
0
0
0
10
% K
% Leu:
0
0
0
30
10
0
40
0
10
10
0
0
0
70
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
10
20
10
0
0
0
70
0
0
0
0
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
0
40
0
0
0
10
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
30
0
0
0
0
% R
% Ser:
50
0
10
30
0
0
0
60
0
0
0
10
20
0
0
% S
% Thr:
10
0
10
10
0
0
0
0
10
0
0
10
50
0
0
% T
% Val:
10
20
0
0
70
30
20
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
20
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _