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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGAP4 All Species: 4.24
Human Site: S209 Identified Species: 10.37
UniProt: Q96P64 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P64 NP_597703.2 663 73070 S209 S Q E D P Q F S V P P T A N T
Chimpanzee Pan troglodytes XP_001141446 439 48772
Rhesus Macaque Macaca mulatta XP_001082744 804 89081 S324 L F T S R K G S D P D K E K K
Dog Lupus familis XP_848466 936 102470 V456 V T L C D N G V L T Y H P S L
Cat Felis silvestris
Mouse Mus musculus Q8BXK8 857 94393 V377 V T L C D N G V L T Y H P S L
Rat Rattus norvegicus Q8CGU4 1186 124419 Y693 N K E W K K K Y V T L S S N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRL1 864 95088 Y380 S D N G V L T Y H P S L H D Y
Zebra Danio Brachydanio rerio Q08CI4 339 38765
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NGC3 995 108026 K470 R S S K S L N K E W K K K Y V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5W7F2 827 92506 Q269 S P N G D G I Q A I G R S S H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.2 56.3 50 N.A. 52.6 28.2 N.A. N.A. N.A. 48.6 22.3 N.A. 29.5 N.A. N.A. N.A.
Protein Similarity: 100 64.5 66.9 58.7 N.A. 62.4 39.2 N.A. N.A. N.A. 59.8 34.2 N.A. 41.7 N.A. N.A. N.A.
P-Site Identity: 100 0 13.3 0 N.A. 0 20 N.A. N.A. N.A. 13.3 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 0 20 13.3 N.A. 13.3 53.3 N.A. N.A. N.A. 20 0 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % A
% Cys: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 30 0 0 0 10 0 10 0 0 10 0 % D
% Glu: 0 0 20 0 0 0 0 0 10 0 0 0 10 0 0 % E
% Phe: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 20 0 10 30 0 0 0 10 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 20 10 0 10 % H
% Ile: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % I
% Lys: 0 10 0 10 10 20 10 10 0 0 10 20 10 10 10 % K
% Leu: 10 0 20 0 0 20 0 0 20 0 10 10 0 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 20 0 0 20 10 0 0 0 0 0 0 20 0 % N
% Pro: 0 10 0 0 10 0 0 0 0 30 10 0 20 0 0 % P
% Gln: 0 10 0 0 0 10 0 10 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 30 10 10 10 10 0 0 20 0 0 10 10 20 30 0 % S
% Thr: 0 20 10 0 0 0 10 0 0 30 0 10 0 0 10 % T
% Val: 20 0 0 0 10 0 0 20 20 0 0 0 0 0 10 % V
% Trp: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 20 0 0 20 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _